Efficient intramolecular general acid catalysis of the hydrolysis of a dialkyl acetal

被引：3

作者：

Brown, CJ ^{[1
]}

Kirby, AJ ^{[1
]}

机构：

[1] UNIV CAMBRIDGE,CHEM LAB,CAMBRIDGE CB2 1EW,ENGLAND

来源：

CHEMICAL COMMUNICATIONS | 1996年 / 20期

关键词：

D O I：

10.1039/cc9960002355

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The hydrolysis of benzaldehyde acetal 3, catalysed by the neighbouring carboxy group, is some 10(5) times faster than that of a comparable system 6, which does not form a strong intramolecular hydrogen bond in the transition state for the reaction.

引用

页码：2355 / 2356

页数：2

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