Validation of the Unified Parkinson's Disease Rating Scale (UPDRS) section I as a screening and diagnostic instrument for apathy in patients with Parkinson's disease

被引：30
|
作者：
Pedersen, Kenn Freddy [1 ,2 ]
Larsen, Jan Petter [1 ,2 ]
Aarsland, Dag [1 ,3 ]
机构：
[1] Norwegian Ctr Movement Disorders, N-4068 Stavanger, Norway
[2] Stavanger Univ Hosp, Dept Neurol, N-4068 Stavanger, Norway
[3] Stavanger Univ Hosp, Psychiat Clin, N-4068 Stavanger, Norway
来源：
PARKINSONISM & RELATED DISORDERS | 2008年 / 14卷 / 03期
关键词：
Parkinson's disease; apathy; motivation/initiative; validity;
D O I：
10.1016/j.parkreldis.2007.07.015
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
We examined the validity of the motivation/initiative item of the Unified Parkinson's Disease Rating Scale (UPDRS) section I as a screening and diagnostic measure for apathy in Parkinson's disease (PD). Fifty-eight patients with PD were evaluated with the UPDRS, the 14-item Apathy Scale (AS), and standardized rating scales of depression and cognitive impairment. Apathy was diagnosed using specific items of the AS together with proposed criteria for apathy. A score of 2 or more on the motivation/initiative item was adequate to screen for apathy, whereas a score of 4 had high diagnostic accuracy at the cost of unacceptable low sensitivity. (c) 2007 Elsevier Ltd. All rights reserved.
引用
收藏
页码：183 / 186
页数：4
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