General principles of identification by mass spectrometry

被引：60

作者：

Milman, Boris L. ^{[1
]}

机构：

[1] Inst Expt Med, St Petersburg 197376, Russia

来源：

TRAC-TRENDS IN ANALYTICAL CHEMISTRY | 2015年 / 69卷

关键词：

Chemical identification; High-resolution mass spectrometry; Mass spectral library; Mass spectrometry; Metrology; Non-target identification; Prediction of spectra; Qualitative analysis; Spectral interpretation; Target identification; TOXICOLOGICALLY RELEVANT DRUGS; FRAGMENTATION TREES; REFERENCE LIBRARY; DATABASE; MS; HYPOTHESES;

D O I：

10.1016/j.trac.2014.12.009

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The review is devoted to chemical identification using mass spectrometry as the most powerful technique of qualitative analysis. The review begins with consideration of basic principles and means of chemical identification. Following are sections covering techniques and instruments and metrological issues. Procedures for identification outlined next are divided into target identification by methods and unknown/non-target analysis. For the latter, information support, such as mass spectral libraries and chemical databases, programs of formula generation and spectral prediction/interpretation, are reviewed. Finally, identification of samples and some general trends are briefly noted. (C) 2014 Elsevier B.V. All rights reserved.

引用

页码：24 / 33

页数：10

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