Fertility of Cryptorchid Testis-An Unsolved Mistery

被引:16
作者
Ciongradi, Carmen Iulia [1 ]
Sarbu, Ioan [1 ]
Halitchi, Codruta Olimpiada Iliescu [2 ]
Benchia, Diana [1 ]
Sarbu, Klara [3 ]
机构
[1] Grigore T Popa Univ Med & Pharm, Dept SurgeryPediatr Surg & Orthoped 2, Iasi 700115, Romania
[2] Grigore T Popa Univ Med & Pharm, Dept Mother & Child Med Pediat, Iasi 700115, Romania
[3] Klara Sarbu MD Off, Targu Neamt, Neamt 615200, Romania
关键词
testis; undescended testis; fertility; cryptorchidism; orchidopexy; spermatogonia; hormonal; GnRH; HUMAN CHORIONIC-GONADOTROPIN; TESTICULAR SPERM EXTRACTION; GERM-CELL MATURATION; NONOBSTRUCTIVE AZOOSPERMIA; UNDESCENDED TESTES; EARLY ORCHIDOPEXY; HORMONAL-CONTROL; BOYS; DESCENT; INFERTILITY;
D O I
10.3390/genes12121894
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Cryptorchidism (undescended testis) is one of the most common diagnoses in the pediatric urologist office. Even in the modern era, there still are a lot of debates regarding the optimal time for surgery related to the expected results in relation with the testicular function, including fertility. The review below intends to clarify issues regarding the impact of cryptorchidism on testicular histology and function, semen analysis, the relation between hormonal and surgical treatment, future fertility, and paternity rate.
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页数:11
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共 65 条
  • [1] ADAMSEN S, 1988, ACTA CHIR SCAND, V154, P529
  • [2] Single subcutaneous administration of chorionic gonadotropin to rats induces a rapid and transient increase in testicular expression of pro-inflammatory cytokines
    Assmus, M
    Svechnikov, K
    Von Euler, M
    Setchell, B
    Sultana, T
    Zetterström, C
    Holst, M
    Kiess, W
    Söder, O
    [J]. PEDIATRIC RESEARCH, 2005, 57 (06) : 896 - 901
  • [3] Insulin-like factor 3 levels in second-trimester amniotic fluid
    Bay, Katrine
    Cohen, Arieh S.
    Jorgensen, Finn Stener
    Jorgensen, Connie
    Lind, Anne Marie
    Skakkebaek, Niels E.
    Andersson, Anna-Maria
    [J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2008, 93 (10) : 4048 - 4051
  • [4] BUSERELIN TREATMENT OF CRYPTORCHIDISM - A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY
    BICA, DTG
    HADZISELIMOVIC, F
    [J]. JOURNAL OF UROLOGY, 1992, 148 (02) : 617 - 621
  • [5] THE BEHAVIOR OF EPIDIDYMIS, PROCESSUS-VAGINALIS AND TESTICULAR DESCENT IN CRYPTORCHID BOYS TREATED WITH BUSERELIN
    BICA, DTG
    HADZISELIMOVIC, F
    [J]. EUROPEAN JOURNAL OF PEDIATRICS, 1993, 152 : S38 - S42
  • [6] Pediatric and Adolescent Oncofertility in Male Patients-From Alpha to Omega
    Bica, Ovidiu
    Sarbu, Ioan
    Ciongradi, Carmen Iulia
    [J]. GENES, 2021, 12 (05)
  • [7] A critical appraisal of the evidence for improved fertility indices in undescended testes after gonadotrophin-releasing hormone therapy and orchidopexy
    Biers, S. M.
    Malone, P. S.
    [J]. JOURNAL OF PEDIATRIC UROLOGY, 2010, 6 (03) : 239 - 246
  • [8] Prepubertal human chorionic gonadotropin injection affects postpubertal germ cell maturation and androgen production in rat testis
    Chandrasekharam, VVSS
    Srinivas, M
    Das, SN
    Jha, P
    Bajpai, M
    Chaki, SP
    Misro, MM
    [J]. UROLOGY, 2003, 62 (03) : 571 - 574
  • [9] Cryptorchidism and its impact on male fertility: a state of art review of current literature
    Chung, Eric
    Brock, Gerald B.
    [J]. CUAJ-CANADIAN UROLOGICAL ASSOCIATION JOURNAL, 2011, 5 (03): : 210 - 214
  • [10] Cortes D, 1998, Scand J Urol Nephrol Suppl, V196, P1