Angiosarcoma of the ovary in an 11 year old girl: Case report and review of the literature

被引:1
作者
Iljazovic, Ermina [1 ]
Tomic, Snjezana [5 ]
Mustedanagic-Mujanovic, Jasminka [1 ]
Karasalihovic, Zinaida [1 ]
Kuljanin, Majda [1 ]
Fatusic, Zlatan [2 ]
Konjic, Elvira [3 ]
Husaric, Edin [3 ]
Latifagic, Amila [3 ]
Arnautalic, Lejla [4 ]
机构
[1] Univ Clin Ctr Tuzla, Dept Pathol, Tuzla 75000, Bosnia & Herceg
[2] Univ Clin Ctr Tuzla, Dept Gynecol & Obstet, Tuzla 75000, Bosnia & Herceg
[3] Univ Clin Ctr Tuzla, Pediat Clin, Tuzla 75000, Bosnia & Herceg
[4] Univ Clin Ctr Tuzla, Clin Radiol & Nucl Med, Tuzla 75000, Bosnia & Herceg
[5] Clin Ctr Split, Dept Pathol, Split 21000, Croatia
关键词
primary angiosarcoma; ovary; childhood; CORD-STROMAL TUMORS; SOFT-TISSUE; CALRETININ; SARCOMAS; INHIBIN;
D O I
暂无
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Sarcomas of the female genital tract in general are rare and ovarian sarcomas comprise less than 1% of ovarian malignancies. In the literature there are 15 reported angiosarcomas of patients 21 year old and younger with no one originated in the ovary. We report a case of ovarian angiosarcoma in an it year old girl, presented with left side hip pain. MRI of abdomen and pelvis confirmed expansive solid and cystic mass occupied both ovaries. Imunohistochemistry staining was performed, CD34, Factor VIII, CD31, in order to confirm the diagnosis. Final diagnosis was angiosarcoma. The patient received 6 cycles of chemotherapy, according to the CWS-2002P protocol. 8 months after the diagnosis was established, there were no signs of any tumors according to the ultrasound, CT scan, and MRI. Although, extremely rare, angiosarcoma can also affect children and this diagnosis should be considered carefully in tumor with rich vascular network, necrosis and brisk mitotic activity. (C) 2011 Association of Basic Medical Sciences of FBIH. All rights reserved
引用
收藏
页码:132 / 136
页数:5
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