New Highly Oxidized Formamidobisabolene-Derived Sesquiterpenes from a Hainan Sponge Axinyssa variabilis

被引:12
作者
Liu, Hai-Li [1 ]
Xue, Duo-Qing [1 ]
Chen, Si-Han [1 ]
Li, Xu-Wen [1 ]
Guo, Yue-Wei [1 ]
机构
[1] Chinese Acad Sci, State Key Lab Drug Res, Shanghai Inst Mat Med, 555 Zu Chong Zhi Rd,Zhangjiang Hitech Pk, Shanghai 201203, Peoples R China
关键词
Bisabolene; Nitrogenous sesquiterpenes; Hainan sponge; Axinyssa variabilis; Biosynthetic pathway; MARINE SPONGES; NATURAL-PRODUCTS; GENUS AXINYSSA;
D O I
10.1002/hlca.201600077
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Two new highly oxidized formamidobisabolene sesquiterpenes (1 and 2), together with seven known related analogues (3 - 9), were isolated from a Hainan sponge Axinyssa variabilis. Their structures were determined by extensive 1D- and 2D-NMR and MS spectra analyses, and by comparison of their spectroscopic data with those of the related model compounds. The plausible biosynthetic relationship between compounds 1 - 9 has also been described.
引用
收藏
页码:650 / 653
页数:4
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