The association between severe menopausal symptoms and engagement with HIV care and treatment in women living with HIV

被引：29

作者：

Solomon, Danielle ^{[1
]}

Sabin, Caroline A. ^{[1
]}

Burns, Fiona ^{[1
,2
]}

Gilson, Richard ^{[1
]}

Allan, Sris ^{[3
]}

de Ruiter, Annamiek ^{[4
,5
]}

Dhairyawan, Rageshri ^{[6
]}

Fox, Julie ^{[4
]}

Gilleece, Yvonne ^{[7
,8
]}

Jones, Rachael ^{[9
]}

Post, Frank ^{[10
]}

Reeves, Iain ^{[11
]}

Ross, Jonathan ^{[12
]}

Ustianowski, Andrew ^{[13
]}

Shepherd, Jane ^{[14
]}

Tariq, S. ^{[1
]}

机构：

[1] UCL, Inst Global Hlth, London, England

[2] Royal Free London NHS Fdn Trust, London, England

[3] Coventry & Warwickshire Partnership NHS Trust, Coventry, W Midlands, England

[4] Guys & St Thomas NHS Fdn Trust, London, England

[5] ViiV Healthcare, Brentford, England

[6] Barking Havering & Redbridge NHS Trust, Romford, Essex, England

[7] Brighton & Sussex Univ Hosp NHS Trust, Brighton, E Sussex, England

[8] Brighton & Sussex Med Sch, Brighton, E Sussex, England

[9] Chelsea & Westminster Hosp NHS Fdn Trust, London, England

[10] Kings Coll Hosp NHS Fdn Trust, London, England

[11] Homerton Univ Hosp NHS Fdn Trust, London, England

[12] Univ Hosp Birmingham NHS Fdn Trust, Birmingham, W Midlands, England

[13] Penine Acute Hosp NHS Trust, North Manchester Gen Hosp, Manchester, Lancs, England

[14] UK Community Advisory Board, London, England

来源：

AIDS CARE-PSYCHOLOGICAL AND SOCIO-MEDICAL ASPECTS OF AIDS/HIV | 2021年 / 33卷 / 01期

基金：

英国惠康基金;

关键词：

Menopause; ageing; women; hiv; adherence; clinic attendance; PERIMENOPAUSAL; ADHERENCE; HEALTH;

D O I：

10.1080/09540121.2020.1748559

中图分类号：

R19 [保健组织与事业（卫生事业管理）];

学科分类号：

摘要：

Using data from the PRIME Study, an observational study of the menopause in women living with HIV in England, we explored the association between menopausal symptoms and: (i) antiretroviral therapy (ART) adherence and (ii) HIV clinic attendance. We measured menopausal symptom severity with the Menopause Rating Scale (MRS, score >= 17 indicating severe symptoms), adherence with the CPCRA Antiretroviral Medication Adherence Self-Report Form, and ascertained HIV clinic attendance via self-report. Odds ratios were obtained using logistic regression. Women who reported severe menopausal symptoms had greater odds of suboptimal ART adherence (adjusted odds ratio (AOR) 2.22; 95% CI 1.13, 4.35) and suboptimal clinic attendance (AOR 1.52; 95% CI 1.01, 2.29). When psychological, somatic and urogenital domains of the MRS were analysed individually there was no association between adherence and severe symptoms (all p > 0.1), however there was an association between suboptimal HIV clinic attendance and severe somatic (AOR 1.98; 95% CI 1.24, 3.16) and psychological (AOR 1.76; 95% CI 1.17, 2.65) symptoms. Severe menopausal symptoms were significantly associated with sub-optimal ART adherence and HIV clinic attendance, however we cannot infer causality, highlighting the need for longitudinal data.

引用

页码：101 / 108

页数：8

共 23 条

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