Transition-metal-free dehydrogenation coupling of pyridinium through a self-promoted hydride transfer process

被引：6

作者：

Shang, Wenbin ^{[1
,3
]}

Li, Shanyong ^{[1
,3
]}

Ding, Yuzhen ^{[2
]}

Pan, Zhiqiang ^{[2
]}

Tong, Xiaogang ^{[2
]}

Xia, Chengfeng ^{[1
,2
]}

机构：

[1] Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, 132 Lanhei Rd, Kunming 650201, Yunnan, Peoples R China

[2] Yunnan Univ, Sch Chem Sci & Technol, Minist Educ, Key Lab Med Chem Nat Resources, 2 North Cuihu Rd, Kunming 650091, Yunnan, Peoples R China

[3] Univ Chinese Acad Sci, Beijing 100049, Peoples R China

来源：

ORGANIC CHEMISTRY FRONTIERS | 2017年 / 4卷 / 09期

基金：

中国国家自然科学基金;

关键词：

C-H FUNCTIONALIZATION; HYDROGEN EVOLUTION REACTION; QUINOLINE N-OXIDES; DIRECT ARYLATION; SELECTIVE ALKENYLATION; ALPHA-ARYLATION; ALKYLATION; DERIVATIVES; PHOTOREDOX; CHEMISTRY;

D O I：

10.1039/c7qo00389g

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A transition-metal-free intramolecular cross dehydrogenation coupling reaction of pyridinium was developed. The C(sp(2))-H/C(sp(2))-H coupling reaction involved an unprecedented intermolecular hydride transfer process from the 1,2-dihydropyridine intermediate to another molecule of pyridinium and formed 1,4-dihydropyridine. Unlike the well-known dehydrogenation coupling proceeded under oxidative conditions, this was the first example of the coupling reaction through a substrate self-promoted hydride transfer process.

引用

页码：1789 / 1793

页数：5

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