Transition-metal-free dehydrogenation coupling of pyridinium through a self-promoted hydride transfer process

被引：6
作者：
Shang, Wenbin [1 ,3 ]
Li, Shanyong [1 ,3 ]
Ding, Yuzhen [2 ]
Pan, Zhiqiang [2 ]
Tong, Xiaogang [2 ]
Xia, Chengfeng [1 ,2 ]
机构：
[1] Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, 132 Lanhei Rd, Kunming 650201, Yunnan, Peoples R China
[2] Yunnan Univ, Sch Chem Sci & Technol, Minist Educ, Key Lab Med Chem Nat Resources, 2 North Cuihu Rd, Kunming 650091, Yunnan, Peoples R China
[3] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
来源：
ORGANIC CHEMISTRY FRONTIERS | 2017年 / 4卷 / 09期
基金：
中国国家自然科学基金;
关键词：
C-H FUNCTIONALIZATION; HYDROGEN EVOLUTION REACTION; QUINOLINE N-OXIDES; DIRECT ARYLATION; SELECTIVE ALKENYLATION; ALPHA-ARYLATION; ALKYLATION; DERIVATIVES; PHOTOREDOX; CHEMISTRY;
D O I：
10.1039/c7qo00389g
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A transition-metal-free intramolecular cross dehydrogenation coupling reaction of pyridinium was developed. The C(sp(2))-H/C(sp(2))-H coupling reaction involved an unprecedented intermolecular hydride transfer process from the 1,2-dihydropyridine intermediate to another molecule of pyridinium and formed 1,4-dihydropyridine. Unlike the well-known dehydrogenation coupling proceeded under oxidative conditions, this was the first example of the coupling reaction through a substrate self-promoted hydride transfer process.
引用
收藏
页码：1789 / 1793
页数：5
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