Improving Sexual Function in People With Chronic Kidney Disease: A Narrative Review of an Unmet Need in Nephrology Research

被引:8
作者
Harrison, Tyrone G. [1 ,2 ]
Skrtic, Marko [3 ,4 ]
Verdin, Nancy E. [5 ]
Lanktree, Matthew B. [6 ]
Elliott, Meghan J. [1 ,2 ]
机构
[1] Univ Calgary, Dept Med, Sect Nephrol, 1403 29 St NW, Calgary, AB T2N 2T9, Canada
[2] Univ Calgary, Dept Community Hlth Sci, Calgary, AB, Canada
[3] Univ Hlth Network, Div Nephrol, Dept Med, Toronto, ON, Canada
[4] Hosp Sick Children, Dept Cell Biol, Toronto, ON, Canada
[5] Univ Calgary, OBrien Inst Publ Hlth, Patient & Community Engagement Res Unit, Calgary, AB, Canada
[6] McMaster Univ, St Josephs Healthcare Hamilton, Div Nephrol, Dept Med, Hamilton, ON, Canada
基金
加拿大健康研究院;
关键词
chronic kidney disease; sexual function; sexual health; narrative review; ERECTILE DYSFUNCTION; RESEARCH PRIORITIES; CARE; DEFINITIONS; PATTERNS; DIALYSIS; OUTCOMES; MODELS; WOMEN; MEN;
D O I
10.1177/2054358120952202
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Purpose of review: Sexual dysfunction occurs commonly in people with chronic kidney disease (CKD) and has been recognized as a research priority. We sought to evaluate the current state of the literature addressing sexual dysfunction in people with CKD and identify barriers and strategies to improve our management of this important symptom. Sources of information: OVID Medline and Google Scholar were searched for English, peer-reviewed studies using keywords and terms related to "Chronic Kidney Disease," "sexuality," and "sexual dysfunction OR function." Methods: In this narrative review, we describe definitions of sexual dysfunction and contributors exacerbated by CKD, barriers to researching sexual dysfunction in people with CKD, and possible avenues for future research. Key findings: Sexual dysfunction is common in people with CKD and results from a combination of kidney disease itself, as well as its associated physical (ie, comorbidities) and nonphysical factors. Barriers to the study of sexual dysfunction in CKD include inconsistent disease definitions, stigma, variable efficacy and safety of established therapies, and evolving gender roles in sexual function. Potential avenues for future research to improve the sexual function in people with CKD may include evaluating the safety and efficacy of established therapies in people with CKD using a variety of observational and interventional study designs, engaging people with CKD and multidisciplinary team members in research, and using implementation science methods to translate what is known about sexual function into clinical practice. Concerted efforts are required to break down barriers and improve sexual function in people with CKD. Patients have identified this as an important research priority, and national networks need to direct efforts to reduce symptom burden. Limitations: This narrative review was limited by a paucity of high-quality studies examining sexual dysfunction specifically in people with kidney disease.
引用
收藏
页数:11
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