Advances in Nanomaterials-Based Carrier System for the Treatment of Breast Cancer

被引:0
作者
Mandadi, Sandhya Rani [1 ,2 ]
Srinivas, Lankalapalli [1 ]
Prasad, V. V. S. Rajendra [2 ]
机构
[1] GITAM Deemed Univ Univ, GITAM Inst Pharm, Dept Pharmaceut, Visakhapatnam 530045, Andhra Pradesh, India
[2] Vishnu Inst Pharmaceut Educ Res, Ctr Mol Canc Res CMCR, Narsapur 502313, Telangana, India
关键词
Breast cancer; nanoparticles; nanoengineered; Anti-Breast cancer drugs; nano-drug delivery system; CELL PROLIFERATION; NANOPARTICLES; TRASTUZUMAB; LIPOSOMES; IMMUNOHISTOCHEMISTRY; DOCETAXEL; DELIVERY; BIOLOGY;
D O I
10.9734/JPRI/2021/v33i46B32982
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Nanotherapeutics for the cure of breast cancer remains unswervingly succeeding and being practiced to eradicate innumerable restrictions of conventional practice obtainable for the supervision of breast cancer. Nanoparticles offer an interdisciplinary extent for exploration in imaging, diagnosis and targeting of breast cancer. Through a progressive physicochemical features and improved bioavailability, they spectacle persistent blood circulation through effective tumor targeting. Nanoparticles remain capable to diminish cytotoxic consequence of the active anticancer medications through amassed cancer cell targeting in contrast to conventional preparations. Several nanoparticles-based preparations remain in the preclinical and clinical phases of progress; amongst them, polymeric drug micelles, liposomes, and dendrimer, remain the utmost common. In this review, we have conferred the role of nanoparticles through detail to oncology, by predominantly aiming on the breast cancer and several nanodelivery systems practiced for targeting action and signaling forces through further intracellular pathways in breast cancer.
引用
收藏
页码:600 / 622
页数:23
相关论文
共 121 条
  • [1] Defining cisplatin incorporation properties in thermosensitive injectable biodegradable hydrogel for sustained delivery and enhanced cytotoxicity
    Abdel-Bar, Hend Mohamed
    Abdel-Reheem, Amal Youssef
    Osman, Rihab
    Awad, Gehanne A. S.
    Mortada, Nahed
    [J]. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2014, 477 (1-2) : 623 - 630
  • [2] A Role for Notch Signalling in Breast Cancer and Endocrine Resistancesssss
    Acar, Ahmet
    Simoes, Bruno M.
    Clarke, Robert B.
    Brennan, Keith
    [J]. STEM CELLS INTERNATIONAL, 2016, 2016
  • [3] Tamoxifen/raloxifene loaded liposomes for oral treatment of breast cancer
    Agardan, N. B. Mutlu
    Degim, Z.
    Yilmaz, S.
    Altintas, L.
    Topal, T.
    [J]. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, 2020, 57
  • [4] The Effectiveness of Raloxifene-Loaded Liposomes and Cochleates in Breast Cancer Therapy
    Agardan, N. Basaran Mutlu
    Degim, Zelihagul
    Yilmaz, Sukran
    Altintas, Levent
    Topal, Turgut
    [J]. AAPS PHARMSCITECH, 2016, 17 (04): : 968 - 977
  • [5] Targeting ligand-activated ErbB2 signaling inhibits breast and prostate tumor growth
    Agus, DB
    Akita, RW
    Fox, WD
    Lewis, GD
    Higgins, B
    Pisacane, PI
    Lofgren, JA
    Tindell, C
    Evans, DP
    Maiese, K
    Scher, HI
    Sliwkowski, MX
    [J]. CANCER CELL, 2002, 2 (02) : 127 - 137
  • [6] A Review of Clinical Translation of Inorganic Nanoparticles
    Anselmo, Aaron C.
    Mitragotri, Samir
    [J]. AAPS JOURNAL, 2015, 17 (05): : 1041 - 1054
  • [7] LIPOSOMES - THE BABRAHAM CONNECTION
    BANGHAM, AD
    [J]. CHEMISTRY AND PHYSICS OF LIPIDS, 1993, 64 (1-3) : 275 - 285
  • [8] Barlow WE, 2002, J NATL CANCER I, V94, P1151
  • [9] DNA Damage, Mutagenesis and Cancer
    Basu, Ashis K.
    [J]. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2018, 19 (04)
  • [10] A historic and scientific review of breast cancer: The next global healthcare challenge
    Becker, Sven
    [J]. INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS, 2015, 131 : S36 - S39