Emission enhancement and application of synthetic green fluorescent protein chromophore analogs

被引：49

作者：

Deng, Hongping ^{[1
]}

Zhu, Xinyuan ^{[1
]}

机构：

[1] Shanghai Jiao Tong Univ, Sch Chem & Chem Engn, State Key Lab Met Matrix Composites, 800 Dongchuan Rd, Shanghai 200240, Peoples R China

来源：

MATERIALS CHEMISTRY FRONTIERS | 2017年 / 1卷 / 04期

基金：

中国国家自然科学基金;

关键词：

INTRAMOLECULAR PROTON-TRANSFER; ULTRAFAST VIBRATIONAL SPECTROSCOPY; AGGREGATION-INDUCED EMISSION; EXCITED-STATE DYNAMICS; GFP-LIKE CHROMOPHORES; CONFINED CHROMOPHORES; OPTICAL-PROPERTIES; STRUCTURAL BASIS; ENERGY-TRANSFER; DERIVATIVES;

D O I：

10.1039/c6qm00148c

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The unique optical properties of genetically encoded green fluorescent protein (GFP) inspire the chemical synthesis, photophysical characterization and application of synthetic GFP chromophore (GFPc) analogs. In this Feature Article, we summarize the recent progress in the fluorescence enhancement and application of synthetic GFPc analogs. In view of fluorescence enhancement, various methods can be classified into physical encapsulation and chemical modification, which can inhibit the chromophores' ultrafast internal conversion. Thus, synthetic GFPc analogs hold great potential as promising candidates in the development of novel sensors or fluorescent probes.

引用

页码：619 / 629

页数：11

共 98 条

[91] Syntheses of highly fluorescent GFP-Chromophore analogues [J].

Wu, Liangxing ;

Burgess, Kevin .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2008, 130 (12) :4089-4096

[92] Synthesis and properties of the red chromophore of the green-to-red photoconvertible fluorescent protein Kaede and its analogs [J].

Yampolsky, Ilia V. ;

Kislukhin, Alexander A. ;

Amatov, Tynchtyk T. ;

Shcherbo, Dmitry ;

Potapov, Victor K. ;

Lukyanov, Sergey ;

Lukyanov, Konstantin A. .

BIOORGANIC CHEMISTRY, 2008, 36 (1-3) :96-104

[93] Synthesis and properties of the chromophore of the asFP595 Chromoprotein from Anemonia sulcata [J].

Yampolsky, IV ;

Remington, SJ ;

Martynov, VI ;

Potapov, VK ;

Lukyanov, S ;

Lukyanov, KA .

BIOCHEMISTRY, 2005, 44 (15) :5788-5793

[94] Chemistry, Biology, and Medicine of Fluorescent Nanomaterials and Related Systems: New Insights into Biosensing, Bioimaging, Genomics, Diagnostics, and Therapy [J].

Yao, Jun ;

Yang, Mei ;

Duan, Yixiang .

CHEMICAL REVIEWS, 2014, 114 (12) :6130-6178

[95] A Unique Family of Rigid Analogues of the GFP Chromophore with Tunable Two-Photon Action Cross-Sections for Biological Imaging [J].

Yuan, Lin ;

Lin, Weiying ;

Chen, Hua ;

Zhu, Sasa ;

He, Longwei .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2013, 52 (38) :10018-10022

[96] Temperature-induced fluorescence enhancement of GFP chromophore containing copolymers for detection of Bacillus thermophilus [J].

Zheng, Yanjie ;

Li, Guolin ;

Deng, Hongping ;

Su, Yue ;

Liu, Jianhua ;

Zhu, Xinyuan .

POLYMER CHEMISTRY, 2014, 5 (07) :2521-2529

[97] Confined chromophores in tobacco mosaic virus to mimic green fluorescent protein [J].

Zhou, Quan ;

Wu, Fengchi ;

Wu, Man ;

Tian, Ye ;

Niu, Zhongwei .

CHEMICAL COMMUNICATIONS, 2015, 51 (82) :15122-15124

[98] Green fluorescent protein (GFP): Applications, structure, and related photophysical behavior [J].

Zimmer, M .

CHEMICAL REVIEWS, 2002, 102 (03) :759-781

← 1 2 3 4 5 6 7 8 9 10 →