Issues related to the decennial tetanus-diphtheria toxoid booster recommendations in adults

被引:23
作者
Gardner, P [1 ]
机构
[1] SUNY Stony Brook, Sch Med, Dept Med, Stony Brook, NY 11794 USA
关键词
D O I
10.1016/S0891-5520(05)70272-5
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
In terms of disease prevention, reduction of adverse reactions, and cost benefit studies, a strong case can be made for a policy that focuses on assuring high levels of primary immunization with tetanus and diphtheria (Td) toxoids and abandons the decennial Td booster in favor of a single midlife booster at age 50-65 years. The addition of acellular pertussis antigens to Td for routine use in adults has potential problems in terms of schedule, cost, and possible adverse reactions. Careful risk/benefit studies are necessary to evaluate its effectiveness and priority.
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页码:143 / +
页数:13
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