JAK2V617F allele burden ≥50% is associated with response to ruxolitinib in persons with MPN-associated myelofibrosis and splenomegaly requiring therapy

被引：47

作者：

Barosi, G. ^{[1
]}

Klersy, C. ^{[2
]}

Villani, L. ^{[1
]}

Bonetti, E. ^{[1
]}

Catarsi, P. ^{[1
]}

Poletto, V. ^{[1
]}

Campanelli, R. ^{[1
]}

Impera, S. ^{[3
]}

Latagliata, R. ^{[4
]}

Viarengo, G. ^{[5
]}

Carolei, A. ^{[1
]}

Massa, M. ^{[1
]}

Musso, M. ^{[6
]}

Crescimanno, A. ^{[6
]}

Gale, R. P. ^{[7
]}

Rosti, V. ^{[1
]}

机构：

[1] IRCCS Policlin S Matteo Fdn, Ctr Study Myelofibrosis, Biotechnol Res Area, Pavia, Italy

[2] IRCCS Policlin S Matteo Fdn, Biometry & Clin Epidemiol, Pavia, Italy

[3] Presidio Osped Garibaldi Nesima, Hematol, Catania, Italy

[4] Univ Rome, Dept Cellular Biotechnol & Hematol, La Sapienza, Italy

[5] IRCCS Policlin S Matteo Fdn, Immunohematol & Transfus Serv, Pavia, Italy

[6] UO Oncol & Trapianto Midollo, Dipartimento Oncol La Maddalena, Palermo, Italy

[7] Imperial Coll London, Haematol Res Ctr, Dept Med, Div Expt Med, London, England

来源：

LEUKEMIA | 2016年 / 30卷 / 08期

关键词：

INTERNATIONAL-WORKING-GROUP; MYELOPROLIFERATIVE NEOPLASMS RESEARCH; TREATMENT IWG-MRT; MYELOID METAPLASIA; CRITERIA;

D O I：

10.1038/leu.2016.45

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：1772 / 1775

页数：6

共 12 条

[11] Revised response criteria for myelofibrosis: International Working Group-Myeloproliferative Neoplasms Research and Treatment (IWG-MRT) and European LeukemiaNet (ELN) consensus report [J].

Tefferi, Ayalew ;

Cervantes, Francisco ;

Mesa, Ruben ;

Passamonti, Francesco ;

Verstovsek, Srdan ;

Vannucchi, Alessandro M. ;

Gotlib, Jason ;

Dupriez, Brigitte ;

Pardanani, Animesh ;

Harrison, Claire ;

Hoffman, Ronald ;

Gisslinger, Heinz ;

Kroeger, Nicolaus ;

Thiele, Juergen ;

Barbui, Tiziano ;

Barosi, Giovanni .

BLOOD, 2013, 122 (08) :1395-1398

[12] A Double-Blind, Placebo-Controlled Trial of Ruxolitinib for Myelofibrosis [J].

Verstovsek, Srdan ;

Mesa, Ruben A. ;

Gotlib, Jason ;

Levy, Richard S. ;

Gupta, Vikas ;

DiPersio, John F. ;

Catalano, John V. ;

Deininger, Michael ;

Miller, Carole ;

Silver, Richard T. ;

Talpaz, Moshe ;

Winton, Elliott F. ;

Harvey, Jimmie H., Jr. ;

Arcasoy, Murat O. ;

Hexner, Elizabeth ;

Lyons, Roger M. ;

Paquette, Ronald ;

Raza, Azra ;

Vaddi, Kris ;

Erickson-Viitanen, Susan ;

Koumenis, Iphigenia L. ;

Sun, William ;

Sandor, Victor ;

Kantarjian, Hagop M. .

NEW ENGLAND JOURNAL OF MEDICINE, 2012, 366 (09) :799-807

← 1 2 →