Copper-Catalyzed Trifluoromethylation of Aryl and Vinyl Boronic Acids with An Electrophilic Trifluoromethylating Reagent

被引：278

作者：

Liu, Tianfei ^{[1
]}

Shen, Qilong ^{[1
]}

机构：

[1] Chinese Acad Sci, Shanghai Inst Organ Chem, Key Lab Organofluorine Chem, Shanghai 200032, Peoples R China

来源：

ORGANIC LETTERS | 2011年 / 13卷 / 09期

基金：

中国国家自然科学基金;

关键词：

REDUCTIVE ELIMINATION; MEDICINAL CHEMISTRY; ARENES; IODINE; ORGANOSTANNANES; BORYLATION; CYANATION; HALIDES; IODANES; AGENT;

D O I：

10.1021/ol2005903

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A copper-catalyzed trifluoromethylation of aryl- and alkenylboronic acids with Togni's reagent was described. The reaction proceeded in good to excellent yields for a range of different substrates including heteroarylboronic acids and substrates with a variety of functional groups under mild reaction conditions.

引用

页码：2342 / 2345

页数：4

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