Impact of Visceral Obesity on Microvascular Invasion in Hepatocellular Carcinoma

被引：6

作者：

Arsenii, Nicolae ^{[1
]}

Piardi, Tullio ^{[2
]}

Diebold, Marie-Daniele ^{[3
]}

Chenard, Marie-Pierrette ^{[4
]}

Drame, Moustapha ^{[5
]}

De Mestier, Louis ^{[1
]}

Hoeffel, Christine ^{[6
]}

Pessaux, Patrick ^{[7
]}

Sommacale, Daniele ^{[2
]}

Thiefin, Gerard ^{[1
]}

机构：

[1] Reims Univ Hosp, Dept Hepatogastroenterol, Reims, France

[2] Reims Univ Hosp, Dept Gen Digest & Endocrine Surg, Reims, France

[3] Reims Univ Hosp, Dept Biopathol, Reims, France

[4] Univ Hosp Strasbourg, Dept Histopathol, Strasbourg, France

[5] Reims Univ Hosp, Dept Res & Innovat, Reims, France

[6] Reims Univ Hosp, Dept Radiol, Reims, France

[7] Univ Hosp Strasbourg, Dept Digest Surg, Strasbourg, France

来源：

CANCER INVESTIGATION | 2016年 / 34卷 / 06期

关键词：

Liver and Billary System Cancer; Angiogenesis; Invasion and Metastasis; Visceral obesity; INTRAHEPATIC RECURRENCE; LIVER-TRANSPLANTATION; RISK-FACTORS; VASCULAR INVASION; ALPHA-FETOPROTEIN; VENOUS INVASION; TUMOR SIZE; RESECTION; CANCER; HEPATECTOMY;

D O I：

10.1080/07357907.2016.1193747

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Background. Our objective was to determine whether visceral obesity is associated with increased microvascular invasion (MVI) in patients surgically treated for hepatocellular carcinoma (HCC). Methods. Data were collected retrospectively in a series of 79 patients treated by surgical resection for HCC, using CT-scan for evaluation of visceral obesity. Results. There was no significant association between visceral obesity and MVI (OR = 1.20 (0.38-3.75), p = 0.75). Independent predictive factors of MVI were moderate/poor differentiation, tumor size above 50mm and underlying cirrhosis. Conclusion. This study did not support the hypothesis that visceral obesity might promote MVI in patients with HCC.

引用

页码：271 / 278

页数：8

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