Intense FAPI Uptake in Inflammation May Mask the Tumor Activity of Pancreatic Cancer in 68Ga-FAPI PET/CT

被引：95
作者：
Luo, Yaping [1 ,2 ]
Pan, Qingqing [1 ,2 ]
Zhang, Wen [3 ,4 ]
Li, Fang [1 ,2 ]
机构：
[1] Chinese Acad Med Sci & Peking Union Med Coll, Dept Nucl Med, Beijing 100730, Peoples R China
[2] Beijing Key Lab Mol Targeted Diag & Therapy Nucl, Beijing 100730, Peoples R China
[3] Chinese Acad Med Sci, Dept Rheumatol, Beijing, Peoples R China
[4] Peking Union Med Coll Hosp, Beijing, Peoples R China
来源：
CLINICAL NUCLEAR MEDICINE | 2020年 / 45卷 / 04期
关键词：
F-18-FDG; Ga-68-FAPI; pancreatic cancer; PET/CT;
D O I：
10.1097/RLU.0000000000002914
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
Contrast CT revealed diffuse enlargement of the pancreas with a suspicious lesion in the uncinate process in a 57-year-old man who presented with jaundice. F-18-FDG PET/CT showed increased radioactivity in the enlarged pancreas with a nodular lesion with even higher uptake in the uncinate process. To differentiate autoimmune pancreatitis and pancreatic cancer, Ga-68-FAPI PET/CT was performed. It revealed intense Ga-68-FAPI uptake in the pancreas, but the FDG-avid lesion in the uncinate process was not shown. The patient was finally diagnosed with pancreatic cancer with tumor-induced pancreatitis with endoscopic ultrasonography-guided biopsy.
引用
收藏
页码：310 / 311
页数：2
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