Expression of E-Selectin in the Skin of Patients with Atopic Dermatitis: Morphometric Study

被引：0
|
作者：
Kulisic, Sandra Marinovic [1 ]
Lipozencic, Jasna [1 ]
Gregurek, Gordana [3 ]
Lackovic, Gordana [3 ]
Juric-Lekic, Gordana [2 ]
机构：
[1] Univ Zagreb, Sch Med, Dept Dermatol & Venereol, Univ Hosp Ctr Zagreb, HR-10000 Zagreb, Croatia
[2] Univ Zagreb, Sch Med, Dept Histol & Embryol, HR-10000 Zagreb, Croatia
[3] Univ Zagreb, Sch Med, Fac Sci, Dept Biol, HR-10000 Zagreb, Croatia
来源：
ACTA DERMATOVENEROLOGICA CROATICA | 2010年 / 18卷 / 03期
关键词：
atopic dermatitis; skin; adhesion molecules; E-selectin; ADHESION MOLECULES;
D O I：
暂无
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
Adhesion molecules may play an important role in the homing of T-cell subsets into allergen-exposed skin of atopic individuals. The aim of this study was to examine the expression of adhesion molecules in atopic dermatitis skin lesions. Biopsies were obtained from lesions in 30 adult patients with atopic dermatitis and 10 healthy adults as controls. Biopsy specimens were studied by immunohistochemistry for the expression of E-selectin in epidermis and dermis cells. Results showed significant changes in the epithelial cell expression of E-selectin, which were especially pronounced in vascular endothelium of the dermis of atopic dermatitis patients.
引用
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页码：141 / 145
页数：5
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