On the Design of Fluorescent Ratiometric Nanosensors

被引：106

作者：

Doussineau, Tristan ^{[1
]}

Schulz, Anja ^{[2
]}

Lapresta-Fernandez, Alejandro ^{[1
]}

Moro, Artur ^{[1
]}

Koersten, Susanne ^{[1
]}

Trupp, Sabine ^{[3
]}

Mohr, Gerhard J. ^{[3
]}

机构：

[1] Univ Jena, Inst Phys Chem, D-07743 Jena, Germany

[2] Dublin City Univ, Opt Sensors Lab, Natl Ctr Sensor Res, Dublin 9, Ireland

[3] Fraunhofer Res Inst Modular Solid State Technol, Workgrp Sensor Mat, D-93053 Regensburg, Germany

来源：

CHEMISTRY-A EUROPEAN JOURNAL | 2010年 / 16卷 / 34期

关键词：

analytical methods; dyes/pigments; fluorescence; nanoparticles; nanosensors; SILICA NANOPARTICLES; OPTICAL NANOSENSORS; PH; SENSORS; BIOSENSORS; PROBES;

D O I：

10.1002/chem.201000829

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Advances in nanoparticle technology have recently offered new tools to the bioanalytical field of research. In particular, new nanoparticle-based sensors have appeared able to give quantitative information about different species (ions, metabolites, biomolecules) in biosamples through ratiometric measurements. This article describes the methodologies developed so far in the design of such nanosensors. In particular, the different approaches to immobilize fluorescent chemosensor dyes to nanoparticles are presented. Concept designs of ratiometric nanosensors in terms of composition and architecture are also described and illustrated with examples taken from the literature.

引用

页码：10290 / 10299

页数：10

共 52 条

[1] Core-shell type dually fluorescent polymer nanoparticles for ratiometric pH-sensing [J].