Curare-like camphor derivatives and their biological activity

被引：8
作者：
Sokolova, A. S. [1 ,2 ]
Morozova, E. A. [1 ]
Vasilev, V. G. [1 ]
Yarovaya, O. I. [1 ,2 ]
Tolstikova, T. G. [1 ,2 ]
Salakhutdinov, N. F. [1 ,2 ]
机构：
[1] Russian Acad Sci, Novosibirsk Organ Chem Inst, Siberian Branch, Novosibirsk 630090, Russia
[2] Novosibirsk State Univ, Novosibirsk 630090, Russia
来源：
RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY | 2015年 / 41卷 / 02期
关键词：
camphor; muscle relaxant activity; rota-rod test; inclined plane test; INHIBITORS; AGENTS;
D O I：
10.1134/S1068162015020156
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The synthesis of symmetric dimeric camphor derivatives containing two quaternary nitrogen atoms was performed and their myorelaxant activity in mice was evaluated. For the comparison, some salts derived from meta- and para-xylylene dibromides were synthesized and their activity was tested.
引用
收藏
页码：178 / 185
页数：8
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