Molecular cloning of PalBH, a mammalian homologue of the Aspergillus atypical calpain PalB

被引：40

作者：

Futai, E

Kubo, T

Sorimachi, H

Suzuki, K

Maeda, T

机构：

[1] Univ Tokyo, Inst Mol & Cellular Biosci, Dept Mol Biol, Lab Mol Struct & Funct,Bunkyo Ku, Tokyo 1130032, Japan

[2] Univ Tokyo, Grad Sch Agr & Life Sci, Dept Appl Biol Chem, Lab Biol Funct,Bunkyo Ku, Tokyo 1138657, Japan

来源：

BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION | 2001年 / 1517卷 / 02期

关键词：

PalBH; PalB; calpain; proteolysis;

D O I：

10.1016/S0167-4781(00)00256-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A mammalian homologue of the Aspergillus atypical calpain PalB, PalBH, was identified and its cDNA sequences were determined in human and mouse. The PalBH mRNA was expressed nearly ubiquitously throughout mammalian tissues. When expressed in COS cells, PalBH was enriched in the nucleus, suggesting its role is distinct from that of conventional calpains. (C) 2001 Elsevier Science B.V. All rights reserved.

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页码：316 / 319

页数：4

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