Recent Advances in Nanomaterial Probes for Optical Biothiol Sensing: A Review

被引:41
作者
Tsogas, George Z. [1 ]
Kappi, Foteini A. [1 ]
Vlessidis, Athanasios G. [1 ]
Giokas, Dimosthenis L. [1 ]
机构
[1] Univ Ioannina, Dept Chem, GR-45110 Ioannina, Greece
关键词
Biological fluids; biothiols; nanoparticles; sensors; spectroscopy; RESONANCE LIGHT-SCATTERING; CAPPED GOLD NANOPARTICLES; LIQUID-CHROMATOGRAPHY ASSAY; HIGHLY FLUORESCENT ANALOGS; SELECTIVE DETERMINATION; SILVER NANOPARTICLES; L-CYSTEINE; HUMAN PLASMA; COLORIMETRIC DETECTION; SENSITIVE DETECTION;
D O I
10.1080/00032719.2017.1329833
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
The determination of biological aminothiols (mainly cysteine, homocysteine, and glutathione) is an important tool in the clinical diagnosis of many disorders and diseases. Therefore, the development of new chemical sensors and probes has attracted considerable attention. Nanomaterials have a profound role in this endeavor since they offer some unique advantages such as lower cost, faster analysis times, and ease of operation compared to classic instrumental techniques such as liquid chromatography and capillary electrophoresis. In this review, we provide a focused outline on the most recent evolvements in optical biothiol sensing using nanomaterials. The most important reaction mechanisms and detection strategies are summarized and compared in terms of their sensitivity and selectivity against various biothiol species. Critical fields for future research and challenges are discussed and elucidated.
引用
收藏
页码:443 / 468
页数:26
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