Progress towards control and elimination of neglected tropical diseases targeted by preventive chemotherapy in Sao Tome e Principe

被引：0
作者：
Byrne, Aisling [1 ]
Rosario, Alzira [2 ]
Ferreira, Maria da Conceicao [3 ]
Trovoada dos Santos, Maria de Jesus [2 ]
Rollinson, David [4 ]
Nery, Susana Vaz [1 ]
机构：
[1] Univ New South Wales, Kirby Inst, Sydney, NSW 1466, Australia
[2] Minist Saude, Programa Controlo Doencas Trop Negligenciadas, Rua Patrice Lumumba, Sao Tome, Sao Tome & Prin
[3] WHO, European Soc Clin Nutr & Metab, Geneva, Switzerland
[4] Nat Hist Museum, Global Schistosomiasis Alliance, London SW7 5BD, England
来源：
TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE | 2022年 / 116卷 / 05期
关键词：
lymphatic filariasis; neglected tropical diseases; preventive chemotherapy; schistosomiasis; soil-transmitted helminths; PARASITIC INFECTIONS; CHILDREN; SCHISTOSOMIASIS;
D O I：
10.1093/trstmh/trab153
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
The Sao Tome e Principe government is committed to achieving neglected tropical disease (NTD) control and elimination as a public health problem by 2025. In 2014, the Ministry of Health led a national survey to determine the prevalence of soil-transmitted helminths (STHs) and schistosomiasis across the country. Following this survey, a preventive chemotherapy (PC) campaign with mebendazole and praziquantel reached 31 501 school-age children in 2015. A follow-up 2017 survey to determine the impact of the intervention showed success in controlling schistosomiasis, as no infections were found, but limited impact on STHs, with prevalence similar to pretreatment levels. The survey also investigated the prevalence of a third NTD, lymphatic filariasis (LF), which was found to be endemic in the country. Since then the Ministry of Health has developed the Strategic Plan for the Fight Against Neglected Tropical Diseases 2019-2025 and identified gaps to be addressed. This narrative review systematises the existing literature reporting on the epidemiology of NTDs for which there are PC programs in Sao Tome e Principe. PubMed was searched for relevant papers that measured the prevalence of LF, schistosomiasis and STHs. Additionally, data provided by the Ministry of Health surveys were analysed. Finally, we discuss current NTD control, including the impact of the coronavirus disease 2019 pandemic and identify priorities for program strengthening and operational research.
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收藏
页码：446 / 453
页数：8
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