Chromatin Remodeling and Associated Changes in Gene Expression Induced By Bone Marrow Stromal Cells Identify Features of High-Risk Multiple Myeloma

被引:0
|
作者
Binder, Moritz [1 ]
Szalat, Raphael E. [1 ]
Fulciniti, Mariateresa [1 ]
Parmigiani, Giovanni [2 ]
Samur, Mehmet K. [3 ]
Munshi, Nikhil C. [1 ,4 ]
机构
[1] Dana Farber Canc Inst, Dept Med Oncol, Boston, MA USA
[2] Dana Farber Canc Inst, Boston, MA USA
[3] Dana Farber Canc Inst, Dept Data Sci, Boston, MA USA
[4] VA Boston Healthcare Syst, Boston, MA USA
关键词
D O I
10.1182/blood-2021-146415
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页数:3
相关论文
共 50 条
  • [31] Gene Expression Profiles Associated with Angiogenesis in Human Site-Specific Bone Marrow Stromal Cells (hBMSCs)
    Du, Yifei
    Zhou, Weina
    Jiang, Hongbin
    Tu, Qisheng
    Chen, Jinkun
    JOURNAL OF BONE AND MINERAL RESEARCH, 2018, 33 : 216 - 216
  • [32] Benefit of complete response in multiple myeloma limited to high-risk subgroup identified by gene expression profiling
    Haessler, Jeffrey
    Shaughnessy, John D., Jr.
    Zhan, Fenghuang
    Crowley, John
    Epstein, Joshua
    van Rhee, Frits
    Anaissie, Elias
    Pineda-Roman, Mauricio
    Zangari, Maurizio
    Hollmig, Klaus
    Mohiuddin, Abid
    Alsayed, Yazan
    Hoering, Antje
    Tricot, Guido
    Barlogie, Bart
    CLINICAL CANCER RESEARCH, 2007, 13 (23) : 7073 - 7079
  • [33] Total Therapy (TT) Studies For Gene Expression Profiling (GEP)-Defined High-Risk Multiple Myeloma
    Heuck, Christoph
    van Rhee, Frits
    Mitchell, Alan
    Rosenthal, Adam
    Waheed, Sarah
    Petty, Nathan M.
    Bailey, Clyde
    Williams, Ryan
    van Laar, Ryan
    Panozzo, Susan B.
    Sawyer, Jeffrey
    Crowley, John
    Barlogie, Bart
    BLOOD, 2013, 122 (21)
  • [34] A high-risk 70-gene signature is not associated with the detection of tumor cell dissemination to the bone marrow
    Walter, Vincent P.
    Taran, Florin-Andrei
    Wallwiener, Markus
    Walter, Christina
    Grischke, Eva-Maria
    Wallwiener, Diethelm
    Brucker, Sara Y.
    Hartkopf, Andreas D.
    BREAST CANCER RESEARCH AND TREATMENT, 2018, 169 (02) : 305 - 309
  • [35] Bone Marrow Stromal Cells Derived MCP-1 Reverses the Inhibitory Effects of Multiple Myeloma Cells on Osteoclastogenesis by Upregulating the RANK Expression
    Liu, Zhiqiang
    Xu, Jingda
    Li, Haiyan
    Zheng, Yuhuan
    He, Jin
    Liu, Huan
    Zhong, Yuping
    Lu, Yong
    Hong, Bangxing
    Zhang, Mingjun
    Lin, Pei
    Du, Juan
    Hou, Jian
    Qian, Jianfei
    Kwak, Larry W.
    Yi, Qing
    Yang, Jing
    PLOS ONE, 2013, 8 (12):
  • [36] A high-risk 70-gene signature is not associated with the detection of tumor cell dissemination to the bone marrow
    Vincent P. Walter
    Florin-Andrei Taran
    Markus Wallwiener
    Christina Walter
    Eva-Maria Grischke
    Diethelm Wallwiener
    Sara Y. Brucker
    Andreas D. Hartkopf
    Breast Cancer Research and Treatment, 2018, 169 : 305 - 309
  • [37] Gene expression profile induced by ovariectomy in bone marrow of mice: A functional approach to identify new candidate genes associated to osteoporosis risk in women
    Pineda, Begona
    Serna, Eva
    Laguna-Fernandez, Andres
    Noguera, Inmaculada
    Panach, Layla
    Hermenegildo, Carlos
    Tarin, Juan J.
    Cano, Antonio
    Angel Garcia-Perez, Miguel
    BONE, 2014, 65 : 33 - 41
  • [38] A validated gene expression model of high-risk multiple myeloma is defined by deregulated expression of genes mapping to chromosome 1
    Shaughnessy, John D.
    Zhan, Fenghuang
    Burington, Bart E.
    Huang, Yongsheng
    Colla, Simona
    Hanamura, Ichiro
    Stewart, James P.
    Kordsmeier, Bob
    Randolph, Christopher
    Williams, David R.
    Xiao, Yan
    Xu, Hongwei
    Epstein, Joshua
    Anaissie, Elias
    Krishna, Somashekar G.
    Cottler-Fox, Michele
    Hollmig, Klaus
    Mohiuddin, Abid
    Pineda-Roman, Mauricio
    Tricot, Guido
    van Rhee, Frits
    Sawyer, Jeffrey
    Alsayed, Yazan
    Walker, Ronald
    Zangari, Maurizio
    Crowley, John
    Barlogie, Bart
    BLOOD, 2007, 109 (06) : 2276 - 2284
  • [39] Multiple myeloma cell adhesion-induced interleukin-6 expression in bone marrow stromal cells involves activation of NF-kappa B
    Chauhan, D
    Uchiyama, H
    Akbarali, Y
    Urashima, M
    Yamamoto, K
    Libermann, TA
    Anderson, KC
    BLOOD, 1996, 87 (03) : 1104 - 1112
  • [40] Interactions Between Multiple Myeloma Cells and Osteocytes Alter Osteocytic Gene Expression: Evidence for Osteocyte-Driven Dysregulation of Bone Remodeling in Multiple Myeloma.
    Delgado-Calle, Jesus
    Plotkin, Lilian
    Bellido, Teresita
    Roodman, G. David
    JOURNAL OF BONE AND MINERAL RESEARCH, 2014, 29 : S374 - S374