Progesterone Exposure and Breast Cancer Risk Understanding the Biological Roots

被引：17

作者：

Joshi, Purna A. ^{[1
]}

Goodwin, Pamela J. ^{[2
]}

Khokha, Rama ^{[1
]}

机构：

[1] Univ Hlth Network, Princess Margaret Canc Ctr, 101 Coll St,Toronto Med Discovery Tower MaRS, Toronto, ON M5G 1L7, Canada

[2] Univ Toronto, Mt Sinai Hosp, Lunenfeld Tanenbaum Res Inst, Toronto, ON, Canada

来源：

JAMA ONCOLOGY | 2015年 / 1卷 / 03期

关键词：

STEM-CELLS; MAMMARY; EXPANSION; CYCLE;

D O I：

10.1001/jamaoncol.2015.0512

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：283 / 285

页数：3

共 11 条

[1] Estrogen plus progestin and breast cancer detection by means of mammography and breast biopsy [J].

Chlebowski, Rowan T. ;

Anderson, Garnet ;

Pettinger, Mary ;

Lane, Dorothy ;

Langer, Robert D. ;

Gillian, Mary Ann ;

Walsh, Brian W. ;

Chen, Chu ;

McTiernan, Anne .

ARCHIVES OF INTERNAL MEDICINE, 2008, 168 (04) :370-377

[2]

Chlebowski RT, JAMA ONCOL, DOI [10.1001/jamaoncol.2015.0494, DOI 10.1001/JAMAONCOL.2015.0494.]

[3] Cellular turnover in the mammary gland is correlated with systemic levels of progesterone and not 17β-estradiol during the estrous cycle [J].

Fata, JE ;

Chaudhary, V ;

Khokha, R .

BIOLOGY OF REPRODUCTION, 2001, 65 (03) :680-688

[4] Expansion of stem cells counteracts age-related mammary regression in compound Timp1/Timp3 null mice [J].

Jackson, Hartland W. ;

Waterhouse, Paul ;

Sinha, Ankit ;

Kislinger, Thomas ;

Berman, Hal K. ;

Khokha, Rama .

NATURE CELL BIOLOGY, 2015, 17 (03) :217-+

[5] Active allies: hormones, stem cells and the niche in adult mammopoiesis [J].

Joshi, Puma A. ;

Di Grappa, Marco A. ;

Khokha, Rama .

TRENDS IN ENDOCRINOLOGY AND METABOLISM, 2012, 23 (06) :299-309

[6] Progesterone induces adult mammary stem cell expansion [J].

Joshi, Purna A. ;

Jackson, Hartland W. ;

Beristain, Alexander G. ;

Di Grappa, Marco A. ;

Mote, Patricia A. ;

Clarke, Christine L. ;

Stingl, John ;

Waterhouse, Paul D. ;

Khokha, Rama .

NATURE, 2010, 465 (7299) :803-807

[7] Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers [J].

Lim, Elgene ;

Vaillant, Francois ;

Wu, Di ;

Forrest, Natasha C. ;

Pal, Bhupinder ;

Hart, Adam H. ;

Asselin-Labat, Marie-Liesse ;

Gyorki, David E. ;

Ward, Teresa ;

Partanen, Audrey ;

Feleppa, Frank ;

Huschtscha, Lily I. ;

Thorne, Heather J. ;

Fox, Stephen B. ;

Yan, Max ;

French, Juliet D. ;

Brown, Melissa A. ;

Smyth, Gordon K. ;

Visvader, Jane E. ;

Lindeman, Geoffrey J. .

NATURE MEDICINE, 2009, 15 (08) :907-913

[8] Morphological changes in breast tissue with menstrual cycle [J].

Ramakrishnan, R ;

Khan, SA ;

Badve, S .

MODERN PATHOLOGY, 2002, 15 (12) :1348-1356

[9] Osteoclast differentiation factor RANKL controls development of progestin-driven mammary cancer [J].

Schramek, Daniel ;

Leibbrandt, Andreas ;

Sigl, Verena ;

Kenner, Lukas ;

Pospisilik, John A. ;

Lee, Heather J. ;

Hanada, Reiko ;

Joshi, Purna A. ;

Aliprantis, Antonios ;

Glimcher, Laurie ;

Pasparakis, Manolis ;

Khokha, Rama ;

Ormandy, Christopher J. ;

Widschwendter, Martin ;

Schett, Georg ;

Penninger, Josef M. .

NATURE, 2010, 468 (7320) :98-+

[10]

Shehata M, 2012, BREAST CANCER RES, V14, pR134

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