Comparative transcriptome meta-analysis reveals a set of genes involved in the responses to multiple pathogens in maize

被引:9
作者
Wang, Yapeng [1 ,2 ,3 ]
Li, Ting [1 ,2 ,3 ]
Sun, Zedan [1 ,2 ,3 ]
Huang, Xiaojian [1 ,2 ,3 ]
Yu, Naibing [1 ,2 ,3 ]
Tai, Huanhuan [1 ,2 ,3 ]
Yang, Qin [1 ,2 ,3 ]
机构
[1] Northwest A&F Univ, State Key Lab Crop Stress Biol Arid Areas, Yangling, Peoples R China
[2] Northwest A&F Univ, Coll Agron, Yangling, Peoples R China
[3] Northwest A&F Univ, Key Lab Maize Biol & Genet Breeding Arid Area Nort, Minist Agr, Yangling, Peoples R China
来源
FRONTIERS IN PLANT SCIENCE | 2022年 / 13卷
基金
中国国家自然科学基金;
关键词
maize; pathogens; meta-analysis; multiple disease resistance; differentially expressed genes (DEGs); QUANTITATIVE DISEASE RESISTANCE; CONFERS RESISTANCE; TRIGGERED IMMUNITY; LEAF-BLIGHT; PLANT; TRANSPORTER; RECOGNITION; LOCUS; CYTOCHROME-P450; CONTRIBUTES;
D O I
10.3389/fpls.2022.971371
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Maize production is constantly threatened by the presence of different fungal pathogens worldwide. Genetic resistance is the most favorable approach to reducing yield losses resulted from fungal diseases. The molecular mechanism underlying disease resistance in maize remains largely unknown. The objective of this study was to identify key genes/pathways that are consistently associated with multiple fungal pathogen infections in maize. Here, we conducted a meta-analysis of gene expression profiles from seven publicly available RNA-seq datasets of different fungal pathogen infections in maize. We identified 267 common differentially expressed genes (co-DEGs) in the four maize leaf infection experiments and 115 co-DEGs in all the seven experiments. Functional enrichment analysis showed that the co-DEGs were mainly involved in the biosynthesis of diterpenoid and phenylpropanoid. Further investigation revealed a set of genes associated with terpenoid phytoalexin and lignin biosynthesis, as well as potential pattern recognition receptors and nutrient transporter genes, which were consistently up-regulated after inoculation with different pathogens. In addition, we constructed a weighted gene co-expression network and identified several hub genes encoding transcription factors and protein kinases. Our results provide valuable insights into the pathways and genes influenced by different fungal pathogens, which might facilitate mining multiple disease resistance genes in maize.
引用
收藏
页数:15
相关论文
共 82 条
[1]   Mutations in a barley cytochrome P450 gene enhances pathogen induced programmed cell death and cutin layer instability [J].
Ameen, Gazala ;
Solanki, Shyam ;
Sager-Bittara, Lauren ;
Richards, Jonathan ;
Tamang, Prabin ;
Friesen, Timothy L. ;
Brueggeman, Robert S. .
PLOS GENETICS, 2021, 17 (12)
[2]   Analysis of quantitative disease resistance to southern leaf blight and of multiple disease resistance in maize, using near-isogenic lines [J].
Belcher, Araby R. ;
Zwonitzer, John C. ;
Cruz, Jose Santa ;
Krakowsky, Mathew D. ;
Chung, Chia-Lin ;
Nelson, Rebecca ;
Arellano, Consuelo ;
Balint-Kurti, Peter J. .
THEORETICAL AND APPLIED GENETICS, 2012, 124 (03) :433-445
[3]   The amino acid permease (AAP) genes CsAAP2A and SlAAP5A/B are required for oomycete susceptibility in cucumber and tomato [J].
Berg, Jeroen A. ;
Hermans, Freddy W. K. ;
Beenders, Frank ;
Abedinpour, Hanieh ;
Vriezen, Wim H. ;
Visser, Richard G. F. ;
Bai, Yuling ;
Schouten, Henk J. .
MOLECULAR PLANT PATHOLOGY, 2021, 22 (06) :658-672
[4]   A maize leucine-rich repeat receptor-like protein kinase mediates responses to fungal attack [J].
Block, Anna K. ;
Tang, Hoang, V ;
Hopkins, Dorothea ;
Mendoza, Jorrel ;
Solemslie, Ryan K. ;
du Toit, Lindsey J. ;
Christensen, Shawn A. .
PLANTA, 2021, 254 (04)
[5]   Biosynthesis and function of terpenoid defense compounds in maize (Zea mays) [J].
Block, Anna K. ;
Vaughan, Martha M. ;
Schmelz, Eric A. ;
Christensen, Shawn A. .
PLANTA, 2019, 249 (01) :21-30
[6]   Synthesis and Functions of Jasmonates in Maize [J].
Borrego, Eli J. ;
Kolomiets, Michael V. .
PLANTS-BASEL, 2016, 5 (04)
[7]   Function, Discovery, and Exploitation of Plant Pattern Recognition Receptors for Broad-Spectrum Disease Resistance [J].
Boutrot, Freddy ;
Zipfel, Cyril .
ANNUAL REVIEW OF PHYTOPATHOLOGY, VOL 55, 2017, 55 :257-286
[8]   Sugar transporters for intercellular exchange and nutrition of pathogens [J].
Chen, Li-Qing ;
Hou, Bi-Huei ;
Lalonde, Sylvie ;
Takanaga, Hitomi ;
Hartung, Mara L. ;
Qu, Xiao-Qing ;
Guo, Woei-Jiun ;
Kim, Jung-Gun ;
Underwood, William ;
Chaudhuri, Bhavna ;
Chermak, Diane ;
Antony, Ginny ;
White, Frank F. ;
Somerville, Shauna C. ;
Mudgett, Mary Beth ;
Frommer, Wolf B. .
NATURE, 2010, 468 (7323) :527-U199
[9]   A flagellin-induced complex of the receptor FLS2 and BAK1 initiates plant defence [J].
Chinchilla, Delphine ;
Zipfel, Cyril ;
Robatzek, Silke ;
Kemmerling, Birgit ;
Nuernberger, Thorsten ;
Jones, Jonathan D. G. ;
Felix, Georg ;
Boller, Thomas .
NATURE, 2007, 448 (7152) :497-U12
[10]   Transgenic expression of plant chitinases to enhance disease resistance [J].
Cletus, Jean ;
Balasubramanian, Vaiyapuri ;
Vashisht, Divya ;
Sakthivel, Natarajan .
BIOTECHNOLOGY LETTERS, 2013, 35 (11) :1719-1732