Vegetables and Their Bioactive Compounds as Anti-Aging Drugs

被引：27
作者：
Mechchate, Hamza [1 ]
El Allam, Aicha [2 ]
El Omari, Nasreddine [3 ]
El Hachlafi, Naoufal [4 ]
Shariati, Mohammad Ali [5 ]
Wilairatana, Polrat [6 ]
Mubarak, Mohammad S. [7 ]
Bouyahya, Abdelhakim [2 ]
机构：
[1] Univ Sidi Mohamed Ben Abdellah USMBA, Fac Sci, Lab Biotechnol Environm Agrifood & Hlth LBEAS, BP 1796, Fes, Morocco
[2] Mohammed V Univ Rabat, Fac Sci, Dept Biol, Lab Human Pathol Biol, Rabat 10106, Morocco
[3] Mohammed V Univ Rabat, Fac Med & Pharm, Lab Histol Embryol & Cytogenet, Rabat 10100, Morocco
[4] Sidi Mohmed Ben Abdellah Univ, Sci & Technol Fac, Microbial Biotechnol & Bioact Mol Lab, Imouzzer Rd,POB 2002, Fes, Morocco
[5] First Cossack Univ, KG Razumovsky Moscow State Univ Technol & Managem, Dept Sci Res, 73 Zemlyanoy Val St, Moscow 109004, Russia
[6] Mahidol Univ, Fac Trop Med, Dept Clin Trop Med, Bangkok 10400, Thailand
[7] Univ Jordan, Dept Chem, Amman 11942, Jordan
来源：
MOLECULES | 2022年 / 27卷 / 07期
关键词：
aging; senescence; wrinkles; vegetables; natural compounds; anti-aging activity; apoptosis; PROGRAMMED CELL-DEATH; CYNARA-SCOLYMUS L; LIFE-SPAN; IN-VITRO; ASPARAGUS-COCHINCHINENSIS; GENOMIC INSTABILITY; CALORIC RESTRICTION; MITOCHONDRIAL-DNA; TELOMERE LENGTH; PROTEIN;
D O I：
10.3390/molecules27072316
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Aging is a continuous process over time that is mainly related to natural alterations in mechanical-biological processes. This phenomenon is due to several factors, including the time and energy of biological processes. Aging can be attributed to biological factors such as oxidative stress, cell longevity, and stem cell senescence. Currently, aging is associated with several diseases, such as neurodegenerative diseases, cancer, and other diseases related to oxidative stress. In addition, certain natural molecules, including those derived from vegetables, have shown the ability to delay the aging process. Their effects are linked to different mechanisms of action, such as tissue regeneration and the activation of longevity and anti-senescence genes. The present work discusses the impact of vegetables, and bioactive compounds isolated from vegetables, against the physiological and pathological aging process and accompanying human diseases.
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页数：33
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