Miniaturized high-performance liquid chromatography instrumentation

被引：60
作者：
Lynch, Kyle B. [1 ]
Chen, Apeng [1 ]
Liu, Shaorong [1 ]
机构：
[1] Univ Oklahoma, Dept Chem & Biochem, 101 Stephenson Pkwy, Norman, OK 73019 USA
来源：
TALANTA | 2018年 / 177卷
关键词：
Electroosmotic pump; Nanoflow; Gradient generator; High performance liquid chromatography; Miniaturized; PACKED CAPILLARY COLUMNS; INDUCED FLUORESCENCE DETECTOR; TRAP MASS-SPECTROMETER; LIGHT-EMITTING DIODE; SOLVENT DELIVERY-SYSTEM; SOLID-PHASE EXTRACTION; DEEP-ULTRAVIOLET RANGE; ELECTROOSMOTIC-PUMP; MICROFLUIDIC CHIP; SMALL MOLECULES;
D O I：
10.1016/j.talanta.2017.09.016
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
Miniaturized high performance liquid chromatography (HPLC) has attracted increasing attention for its potential in high-throughput analyses and point-of-care applications. In this review we highlight the recent advancements in HPLC system miniaturization. We focus on the major components that constitute these instruments along with their respective advantages and drawbacks as well as present a few representative miniaturized HPLC systems. We discuss briefly some of the applications and also anticipate the future development trends of these instrumental platforms.
引用
收藏
页码：94 / 103
页数：10
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