Artificial intelligence software for diagnosing intracranial arterial occlusion in patients with acute ischemic stroke

被引：18

作者：

Fasen, Bram A. C. M. ^{[1
]}

Berendsen, Ralph C. M. ^{[2
]}

Kwee, Robert M. ^{[1
]}

机构：

[1] Zuyderland Med Ctr, Dept Radiol, Henri Dunantstr 5, NL-6419 PC Heerlen Sittard Geleen, Netherlands

[2] Zuyderland Med Ctr, Dept Med Phys, Heerlen Sittard Geleen, Netherlands

来源：

NEURORADIOLOGY | 2022年 / 64卷 / 08期

关键词：

Stroke; Computed tomography angiography; Artificial intelligence; Software; Sensitivity and specificity; CT ANGIOGRAPHY;

D O I：

10.1007/s00234-022-02912-1

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Purpose To evaluate the diagnostic performance of AI software in diagnosing intracranial arterial occlusions in the proximal anterior circulation at CT angiography (CTA) and to compare it to manual reading performed in clinical practice. Methods Patients with acute ischemic stroke underwent CTA to detect arterial occlusion in the proximal anterior circulation. Retrospective review of CTA scans by two neuroradiologists served as reference standard. Sensitivity and specificity of AI software (StrokeViewer) were compared to those of manual reading using the McNemar test. The proportions of correctly detected occlusions in the distal internal carotid artery and/or M1 segment of the middle cerebral artery (large vessel occlusion [LVO]) and in the M2 segment of the middle cerebral artery (medium vessel occlusion [MeVO]) were calculated. Results Of the 474 patients, 75 (15.8%) had an arterial occlusion in the proximal anterior circulation according to the reference standard. Sensitivity of StrokeViewer software was not significantly different compared to that of manual reading (77.3% vs. 78.7%, P = 1.000). Specificity of StrokeViewer software was significantly lower than that of manual reading (88.5% vs. 100%, P < 0.001). StrokeViewer software correctly identified 40 of 42 LVOs (95.2%) and 18 of 33 MeVOs (54.5%). StrokeViewer software detected 8 of 16 (50%) intracranial arterial occlusions which were missed by manual reading. Conclusion The current AI software detected intracranial arterial occlusion with moderate sensitivity and fairly high specificity. The AI software may detect additional occlusions which are missed by manual reading. As such, the use of AI software may be of value in clinical stroke care.

引用

页码：1579 / 1583

页数：5

共 18 条

[1] Fast Automatic Detection of Large Vessel Occlusions on CT Angiography [J].

Amukotuwa, Shalini ;

Straka, Matus ;

Dehkharghani, Seena ;

Bammer, Roland .

STROKE, 2019, 50 (12) :3431-3438

[2] Brain CT perfusion improves intracranial vessel occlusion detection on CT angiography [J].

Becks, Marinus J. ;

Manniesing, Rashindra ;

Vister, Jeroen ;

Pegge, Sjoert A. H. ;

Steens, Stefan C. A. ;

van Dijk, Ewoud J. ;

Prokop, Mathias ;

Meijer, Frederick J. A. .

JOURNAL OF NEURORADIOLOGY, 2019, 46 (02) :124-129

[3] A Randomized Trial of Intraarterial Treatment for Acute Ischemic Stroke [J].

Berkhemer, O. A. ;

Fransen, P. S. S. ;

Beumer, D. ;

van den Berg, L. A. ;

Lingsma, H. F. ;

Yoo, A. J. ;

Schonewille, W. J. ;

Vos, J. A. ;

Nederkoorn, P. J. ;

Wermer, M. J. H. ;

van Walderveen, M. A. A. ;

Staals, J. ;

Hofmeijer, J. ;

van Oostayen, J. A. ;

Nijeholt, G. J. Lycklama A. ;

Boiten, J. ;

Brouwer, P. A. ;

Emmer, B. J. ;

de Bruijn, S. F. ;

van Dijk, L. C. ;

Kappelle, L. J. ;

Lo, R. H. ;

Van Dijk, E. J. ;

de Vries, J. ;

de Kort, P. L. M. ;

van Rooij, W. J. J. ;

van den Berg, J. S. P. ;

van Hasselt, B. A. A. M. ;

Aerden, L. A. M. ;

Dallinga, R. J. ;

Visser, M. C. ;

Bot, J. C. J. ;

Vroomen, P. C. ;

Eshghi, O. ;

Schreuder, T. H. C. M. L. ;

Heijboer, R. J. J. ;

Keizer, K. ;

Tielbeek, A. V. ;

den Hertog, H. M. ;

Gerrits, D. G. ;

van den Berg-Vos, R. M. ;

Karas, G. B. ;

Steyerberg, E. W. ;

Flach, H. Z. ;

Marquering, H. A. ;

Sprengers, M. E. S. ;

Jenniskens, S. F. M. ;

Beenen, L. F. M. ;

van den Berg, R. ;

Koudstaal, P. J. .

NEW ENGLAND JOURNAL OF MEDICINE, 2015, 372 (01) :11-20

[4]

Bossuyt PM, 2015, BMJ-BRIT MED J, V351, DOI [10.1136/bmj.h5527, 10.1373/clinchem.2015.246280, 10.1148/radiol.2015151516]

[5] High-Performance Automated Anterior Circulation CT Angiographic Clot Detection in Acute Stroke: A Multireader Comparison [J].

Dehkharghani, Seena ;

Lansberg, Maarten ;

Venkatsubramanian, Chitra ;

Cereda, Carlo ;

Lima, Fabricio ;

Coelho, Henrique ;

Rocha, Felipe ;

Qureshi, Abid ;

Haerian, Hafez ;

Mont'Alverne, Francisco ;

Copeland, Karen ;

Heit, Jeremy .

RADIOLOGY, 2021, 298 (03) :665-670

[6] CT Angiography in Evaluating Large-Vessel Occlusion in Acute Anterior Circulation Ischemic Stroke: Factors Associated with Diagnostic Error in Clinical Practice [J].

Fasen, B. A. C. M. ;

Heijboer, R. J. J. ;

Hulsmans, F. -J. H. ;

Kwee, R. M. .

AMERICAN JOURNAL OF NEURORADIOLOGY, 2020, 41 (04) :607-611

[7] Diagnostic performance of single-phase CT angiography in detecting large vessel occlusion in ischemic stroke: A systematic review [J].

Fasen, Bram A. C. M. ;

Heijboer, Roeland J. J. ;

Hulsmans, Frans-Jan H. ;

Kwee, Robert M. .

EUROPEAN JOURNAL OF RADIOLOGY, 2021, 134

[8] Radiology workload in clinical implementation of thrombectomy for acute ischemic stroke: experience from The Netherlands [J].

Fasen, Bram A. C. M. ;

Heijboer, Roeland J. J. ;

Hulsmans, Frans-Jan H. ;

Kwee, Robert M. .

NEURORADIOLOGY, 2020, 62 (07) :877-882

[9] Complications of Modern Diagnostic Cerebral Angiography in an Academic Medical Center [J].

Fifi, Johanna T. ;

Meyers, Philip M. ;

Lavine, Sean D. ;

Cox, Virginia ;

Silverberg, Lynn ;

Mangla, Sundeep ;

Pile-Spellman, John .

JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY, 2009, 20 (04) :442-447

[10] Randomized Assessment of Rapid Endovascular Treatment of Ischemic Stroke [J].

Goyal, M. ;

Demchuk, A. M. ;

Menon, B. K. ;

Eesa, M. ;

Rempel, J. L. ;

Thornton, J. ;

Roy, D. ;

Jovin, T. G. ;

Willinsky, R. A. ;

Sapkota, B. L. ;

Dowlatshahi, D. ;

Frei, D. F. ;

Kamal, N. R. ;

Montanera, W. J. ;

Poppe, A. Y. ;

Ryckborst, K. J. ;

Silver, F. L. ;

Shuaib, A. ;

Tampieri, D. ;

Williams, D. ;

Bang, O. Y. ;

Baxter, B. W. ;

Burns, P. A. ;

Choe, H. ;

Heo, J. -H. ;

Holmstedt, C. A. ;

Jankowitz, B. ;

Kelly, M. ;

Linares, G. ;

Mandzia, J. L. ;

Shankar, J. ;

Sohn, S. -I. ;

Swartz, R. H. ;

Barber, P. A. ;

Coutts, S. B. ;

Smith, E. E. ;

Morrish, W. F. ;

Weill, A. ;

Subramaniam, S. ;

Mitha, A. P. ;

Wong, J. H. ;

Lowerison, M. W. ;

Sajobi, T. T. ;

Hill, M. D. .

NEW ENGLAND JOURNAL OF MEDICINE, 2015, 372 (11) :1019-1030

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