Production of polyhydroxy fatty acids from linoleic acid by Clavibacter sp. ALA2

被引：21
作者：
Hou, CT [1 ]
Gardner, H [1 ]
Brown, W [1 ]
机构：
[1] USDA ARS, Natl Ctr Agr Utilizat Res, Peoria, IL 61604 USA
来源：
JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY | 1998年 / 75卷 / 11期
关键词：
biocatalysis; biotransformation; enzymes; hydroxy unsaturated fatty acids; microbes;
D O I：
10.1007/s11746-998-0082-z
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
Hydroxy fatty acids are important industrial materials. We isolated a microbial culture, Clavibacter sp. ALA2, which converts linoleic acid to many polyhydroxy fatty acids. Structures of the products were determined as: 12,13,17-trihydroxy-9(Z)-octadecenoic (THOA, main product), 12-[5-ethyl-2-tetrahydrofuranyl]-7,12-dihydroxy-9(Z)-dodecenoic (ETDDA), and 12-[5-ethyl-2-tetrahydrofuranyl]-12-hydroxy-9(Z)-dodecenoic (ETHDA) acid. The yield of THOA was 25% and the relative amount of the products were THOA/ETDDA/ETHDA = 9:1.3:1. The structures of the hydroxy unsaturated fatty acids resemble those of plant self-defense substances.
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收藏
页码：1483 / 1487
页数：5
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