First results of a refeeding program in a psychiatric intensive care unit for patients with extreme anorexia nervosa

被引:21
作者
Born, Christoph [1 ]
de la Fontaine, Larissa [1 ]
Winter, Bettina [1 ]
Mueller, Norbert [1 ]
Schaub, Annette [1 ]
Fruestuck, Clemens [1 ]
Schuele, Cornelius [1 ]
Voderholzer, Ulrich [2 ]
Cuntz, Ulrich [2 ]
Falkai, Peter [1 ]
Meisenzahl, Eva [1 ]
机构
[1] Univ Munich, Dept Psychiat, D-80336 Munich, Germany
[2] Schoen Klin Roseneck, Prien Am Chiemsee, Germany
关键词
Eating disorders; Anorexia nervosa; Refeeding; Percutaneous gastric feeding tube; High caloric solution; CENTRAL PONTINE MYELINOLYSIS; ADOLESCENT GIRLS; EATING-DISORDERS; BODY-WEIGHT; FOLLOW-UP; EFFICACY; MORTALITY; EPIDEMIC;
D O I
10.1186/s12888-015-0436-7
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Background: Anorexia nervosa (AN) is associated with a high mortality rate. This study describes a compulsory re-feeding program established in Munich for extremely underweight patients. Methods: The contract between the patient and the therapeutic team included mandatory inpatient status, establishment of guardianship and compulsory re-feeding with a percutaneous gastric feeding tube, as indicated. The predefined target was a body mass index (BMI) of 17 kg/m(2). Data on the first 68 patients with AN are presented. Results: 65 (95.6%) patients were female and mean age at admission was 26.5 +/- 8.5 years. BMI increased from 12.3 +/- 1.4 kg/m(2) at admission to 16.7 +/- 1.7 kg/m(2) at discharge. Thirty-two (47.1%) patients had the restrictive subtype (ANR) and 36 (52.9%) had the binging and purging subtype (ANBP). Duration of illness before admission (p = .004), days of treatment until discharge (p = .001) and weight increase (p = .02) were significantly different between subgroups in favor of patients with ANR. Also, seasonal differences could be found. Comparison of feeding methods showed that percutaneous tube feeding was superior. Almost half of the patients were treated with psychotropic medication. To date, however, the number of patients included in this program is too small to assess rare complications of this acute treatment program and long term outcomes of AN. Conclusions: An intensive care program for severely ill AN patients has been successfully established. Besides averting physical harm in the short term, this program was designed to enable these patients to participate in more sophisticated psychotherapeutic programs afterwards. To our knowledge, this is the first such program that regularly uses percutaneous feeding tubes.
引用
收藏
页数:7
相关论文
共 40 条
  • [1] Central pontine myelinolysis in a patient with anorexia nervosa
    Amann, B
    Schäfer, M
    Sterr, A
    Arnold, S
    Grunze, H
    [J]. INTERNATIONAL JOURNAL OF EATING DISORDERS, 2001, 30 (04) : 462 - 466
  • [2] [Anonymous], PSYCHOL MED
  • [3] [Anonymous], DIAGN THER ESSSTR
  • [4] Olanzapine in the treatment of low body weight and obsessive thinking in women with anorexia nervosa: A randomized, double-blind, placebo-controlled trial
    Bissada, Hany
    Tasca, Giorgio A.
    Barber, Ann Marie
    Bradwejn, Jacques
    [J]. AMERICAN JOURNAL OF PSYCHIATRY, 2008, 165 (10) : 1281 - 1288
  • [5] Casiero Deena, 2006, Cardiol Rev, V14, P227
  • [6] Meta analysis on the efficacy of pharmacotherapy versus placebo on anorexia nervosa
    de Vos J.
    Houtzager L.
    Katsaragaki G.
    van de Berg E.
    Cuijpers P.
    Dekker J.
    [J]. Journal of Eating Disorders, 2 (1)
  • [7] Clinical efficacy and safety of parenteral nutrition in adolescent girls with anorexia nervosa
    Diamanti, A.
    Basso, M. S.
    Castro, M.
    Bianco, G.
    Ciacco, E.
    Calce, A.
    Caramadre, A. M.
    Noto, C.
    Gambarara, M.
    [J]. JOURNAL OF ADOLESCENT HEALTH, 2008, 42 (02) : 111 - 118
  • [8] Seasonal BMI Differences Between Restrictive and Purging Anorexia Nervosa Subtypes
    Fraga, Angela
    Caggianesse, Veronica
    Carrera, Olaia
    Graell, Montserrat
    Morande, Gonzalo
    Gutierrez, Emilio
    [J]. INTERNATIONAL JOURNAL OF EATING DISORDERS, 2015, 48 (01) : 35 - 41
  • [9] Severe anorexia nervosa: Outcomes from a medical stabilization unit
    Gaudiani, Jennifer L.
    Sabel, Allison Lee
    Mascolo, Margherita
    Mehler, Philip S.
    [J]. INTERNATIONAL JOURNAL OF EATING DISORDERS, 2012, 45 (01) : 85 - 92
  • [10] Specialized refeeding treatment for anorexia nervosa patients suffering from extreme undernutrition
    Gentile, Maria Gabriella
    Pastorelli, Paola
    Ciceri, Raffaella
    Manna, Giulia Maria
    Collimedaglia, Simona
    [J]. CLINICAL NUTRITION, 2010, 29 (05) : 627 - 632