The influence of demographic and disease-related factors on health-related quality of life in patients with ulcerative colitis

被引:69
作者
Hjortswang, H [1 ]
Järnerot, G
Curman, B
Sandberg-Gertzén, H
Tysk, C
Blomberg, B
Almer, S
Ström, M
机构
[1] Linkoping Univ Hosp, Dept Gastroenterol & Endocrinol, Div Gastroenterol & Hepatol, S-58185 Linkoping, Sweden
[2] Orebro Univ Hosp, Dept Med, Div Gastroenterol, Orebro, Sweden
关键词
inflammatory bowel disease; health; health-related quality of life; quality of life;
D O I
10.1097/00042737-200309000-00012
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Objective The aims of this study were to analyse the health-related quality of life of patients with ulcerative colitis and to assess in what way demographic and disease-related factors influence patients' experiences of this, in order to interpret the results of health-related quality of life assessment more correctly. Patients and methods We carried out a cross-sectional evaluation of 300 consecutive patients with ulcerative colitis from the catchment areas of Linkoping University Hospital and Orebro University Hospital in Sweden. Health-related quality of life was measured using four questionnaires: the IBDQ the RFIPC, the SF-36 and the PGWB. Disease activity was evaluated using a one-week symptom diary, blood tests and rigid sigmoidoscopy. Demographic factors (gender, age, civil status, educational level), disease-related factors (disease duration, disease extent, disease activity) and presence of co-morbidity were obtained. Results Health-related quality of life was mainly impaired in the psychological and social areas and to a much lesser degree in physical areas. Patients with relapse had significantly more disease-related worries and concerns (the RFIPC), more impaired social functioning (the IBDQ and SF-36), and a lower feeling of well being (the IBDQ, the SF-36 and the PGWB). However, their physical function (SF-36) was no worse than patients in remission. Besides the symptom burden of the current disease, co-morbidity and female gender were associated with a lower health-related quality of life. Conclusion To correctly interpret health-related quality of life assessments, it is necessary to consider co-morbidity and gender distribution in addition to the symptom burden of the disease studied. (C) 2003 Lippincott Williams Wilkins.
引用
收藏
页码:1011 / 1020
页数:10
相关论文
共 31 条
  • [1] VARIATION BETWEEN OBSERVERS IN DESCRIBING MUCOSAL APPEARANCES IN PROCTOCOLITIS
    BARON, JH
    CONNELL, AM
    LENNARDJONES, JE
    [J]. BRITISH MEDICAL JOURNAL, 1964, 1 (5374): : 89 - +
  • [2] Influence of inflammatory bowel disease on different dimensions of quality of life
    Casellas, F
    López-Vivancos, J
    Badia, X
    Vilaseca, J
    Malagelada, JR
    [J]. EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, 2001, 13 (05) : 567 - 572
  • [3] Colombel JF, 1996, GASTROEN CLIN BIOL, V20, P1071
  • [4] Inflammatory bowel disease questionnaire: Cross-cultural adaptation and further validation
    deBoer, AGEM
    Wijker, W
    Bartelsman, JFW
    deHaes, HCJM
    [J]. EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, 1995, 7 (11) : 1043 - 1050
  • [5] HEALTH-RELATED QUALITY OF LIFE IN INFLAMMATORY BOWEL-DISEASE - FUNCTIONAL STATUS AND PATIENT WORRIES AND CONCERNS
    DROSSMAN, DA
    PATRICK, DL
    MITCHELL, CM
    ZAGAMI, EA
    APPELBAUM, MI
    [J]. DIGESTIVE DISEASES AND SCIENCES, 1989, 34 (09) : 1379 - 1386
  • [6] THE RATING FORM OF IBD PATIENT CONCERNS - A NEW MEASURE OF HEALTH-STATUS
    DROSSMAN, DA
    LESERMAN, J
    LI, ZM
    MITCHELL, CM
    ZAGAMI, EA
    PATRICK, DL
    [J]. PSYCHOSOMATIC MEDICINE, 1991, 53 (06): : 701 - 712
  • [7] Dupuy H.J., 1984, ASSESSMENT QUALITY L, P170
  • [8] Quality of life in patients with upper gastrointestinal symptoms: Results from the Domestic/International Gastroenterology Surveillance Study (DIGEST)
    Enck, P
    Dubois, D
    Marquis, P
    [J]. SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 1999, 34 : 48 - 54
  • [9] HEALTH-STATUS IN INFLAMMATORY BOWEL-DISEASE - BIOLOGICAL AND BEHAVIORAL CONSIDERATIONS
    GARRETT, JW
    DROSSMAN, DA
    [J]. GASTROENTEROLOGY, 1990, 99 (01) : 90 - 96
  • [10] TREATMENT OF LEFT-SIDED ULCERATIVE-COLITIS WITH 4-AMINOSALICYLIC ACID ENEMAS - A DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL
    GINSBERG, AL
    BECK, LS
    MCINTOSH, TM
    NOCHOMOVITZ, LE
    [J]. ANNALS OF INTERNAL MEDICINE, 1988, 108 (02) : 195 - 199