Gram-type differentiation of bacteria with 2D hollow photonic crystal cavities

被引：33

作者：

Therisod, R. ^{[1
]}

Tardif, M. ^{[2
,3
]}

Marcoux, P. R. ^{[4
]}

Picard, E. ^{[3
]}

Jager, J. -B. ^{[3
]}

Hadji, E. ^{[3
]}

Peyrade, D. ^{[2
]}

Houdre, R. ^{[1
]}

机构：

[1] Ecole Polytech Fed Lausanne, Inst Phys, Stn 3, CH-1015 Lausanne, Switzerland

[2] Univ Grenoble Alpes, CNRS, LTM Micro & Nanotechnol Hlth, F-38054 Grenoble 9, France

[3] Univ Grenoble Alpes, CEA, PHELIQS, INAC,Lab SINAPS, F-38000 Grenoble 9, France

[4] Univ Grenoble Alpes, CEA, LETI, Minatec Campus,17 Ave Martyrs, F-38054 Grenoble 9, France

来源：

APPLIED PHYSICS LETTERS | 2018年 / 113卷 / 11期

基金：

瑞士国家科学基金会;

关键词：

MANIPULATION; FABRICATION;

D O I：

10.1063/1.5037849

中图分类号：

O59 [应用物理学];

学科分类号：

摘要：

Fast and label-free techniques to analyze viruses and bacteria are of crucial interest in biological and bio-medical applications. For this purpose, optofluidic systems based on the integration of photonic structures with microfluidic layers were shown to be promising tools for biological analysis, thanks to their small footprint and to their ability to manipulate objects using low powers. In this letter, we report on the optical trapping of living bacteria in a 2D silicon hollow photonic crystal cavity. This structure allows for the Gram-type differentiation of bacteria at the single cell scale, in a fast, label-free, and non-destructive way. (C) 2018 Author(s).

引用

页数：5