A Trifluoromethylcarbene Source

被引：44

作者：

Duan, Yaya ^{[1
]}

Lin, Jin-Hong ^{[1
]}

Xiao, Ji-Chang ^{[1
]}

Gu, Yu-Cheng ^{[2
]}

机构：

[1] Chinese Acad Sci, Shanghai Inst Organ Chem, Key Lab Organofluorine Chem, 345 Lingling Rd, Shanghai 200032, Peoples R China

[2] Syngenta, Jealotts Hill Int Res Ctr, Bracknell RG42 6EY, Berks, England

来源：

ORGANIC LETTERS | 2016年 / 18卷 / 10期

关键词：

DIASTEREOSELECTIVE SYNTHESIS; CATALYZED CYCLOPROPANATION; SELECTIVE OLEFINATION; IRON PORPHYRIN; ALDEHYDES; DIFLUOROCARBENE; FLUORINE; IMIDAZOPYRIDINES; DECOMPOSITION;

D O I：

10.1021/acs.orglett.6b01042

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The trifluoromethylcarbene (:CHCF3) was found to be conveniently generated from (2,2,2-trifluoroethyl)diphenyl-sulfonium triflate (Ph2S+CH2CF3 -OTf, which was successfully applied in Fe-catalyzed cyclopropanation of olefins, giving the corresponding trifluoromethylated cyclopropanes in high yields.

引用

页码：2471 / 2474

页数：4

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