Factors Associated with Mortality among Elderly People in the COVID-19 Pandemic (SARS-CoV-2): A Systematic Review and Meta-Analysis

被引:42
作者
Alves, Vicente Paulo [1 ,2 ]
Casemiro, Francine Golghetto [3 ]
de Araujo, Bruno Gedeon [1 ]
de Souza Lima, Marcos Andre [1 ]
de Oliveira, Rayssa Silva [1 ]
de Souza Fernandes, Fernanda Tamires [1 ]
Campos Gomes, Ana Vitoria [1 ]
Gregori, Dario [2 ]
机构
[1] Univ Catolica Brasilia, Stricto Sensu Grad Program Gerontol Med, BR-71966700 Taguatinga, Brazil
[2] Padova Univ, Unit Biostat Epidemiol & Publ Hlth, I-35122 Padua, Italy
[3] Univ Sao Paulo, Ribeirao Preto Sch Nursing, BR-14040902 Sao Paulo, Brazil
关键词
SARS-CoV-2; COVID-19; non-communicable chronic diseases (NCCDs); clinical features; institutionalized or hospitalized elderly; meta-analysis;
D O I
10.3390/ijerph18158008
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
The objective of this meta-analysis was to evaluate the factors associated with the mortality of elderly Italians diagnosed with coronavirus who resided in institutions or who were hospitalized because of the disease. Methods: A systematic review following the recommendations of The Joanna Briggs Institute (JBI) was carried out, utilizing the PEO strategy, i.e., Population, Exposure and Outcome. In this case, the population was the elderly aged over 65 years old, the exposure referred to the SARS-CoV-2 pandemic and the outcome was mortality. The National Center for Biotechnology Information (NCBI/PubMed), Latin American and Caribbean Literature in Health Sciences (LILACS), Excerpta Medica Database (EMBASE) and Cumulative Index to Nursing and Allied Health Literature (CINAHL) databases were used until 31 July 2020. Results: Five Italian studies were included in this meta-analysis, with the number of elderly people included varying between 18 and 1591 patients. The main morbidities presented by the elderly in the studies were dementia, diabetes, chronic kidney disease and hypertension. Conclusions: The factors associated with the mortality of elderly Italian people diagnosed with SARS-CoV-2 who lived in institutions or who were hospitalized because of the disease were evaluated. It was found that dementia, diabetes, chronic kidney disease and hypertension were the main diagnosed diseases for mortality in elderly people with COVID-19.
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页数:9
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