Photocatalytic Aerobic Coupling of Azaarenes and Alkanes via Nontraditional Cl• Generation

被引：22

作者：

Bhakat, Manotosh ^{[1
]}

Khatua, Bitasik ^{[1
]}

Guin, Joyram ^{[1
]}

机构：

[1] Indian Assoc Cultivat Sci, Sch Chem Sci, Kolkata 700032, India

来源：

ORGANIC LETTERS | 2022年 / 24卷 / 29期

关键词：

SUPEROXIDE ANION; H ALKYLATION; HETEROARENES; OXYGEN; ION;

D O I：

10.1021/acs.orglett.2c01784

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Herein, we demonstrate a nonconventional photo-catalytic generation of Cl-center dot from a common chlorinated solvent, dichloroethane, under aerobic conditions and its successful utilization toward the cross-dehydrogenative coupling of alkanes and azaarenes via hydrogen atom transfer with Cl-center dot. The process is free from chloride salt, toxic oxidant, and UV light. It is applicable to a broad spectrum of substrates. The proposed mechanism involving Cl-center dot is supported by a series of mechanistic investigations.

引用

页码：5276 / 5280

页数：5

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