Jekyll & Hyde: Evolution of a superfamily

被引：6
作者：
Martinis, Susan A. [1 ]
Pang, Yan Ling Joy [1 ]
机构：
[1] Univ Illinois, Dept Biochem, Urbana, IL 61801 USA
来源：
CHEMISTRY & BIOLOGY | 2007年 / 14卷 / 12期
关键词：
D O I：
10.1016/j.chembiol.2007.12.001
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Aminoacyl-tRNA synthetase mutations have been linked to neurological diseases, but aminoacylation may be unaffected. This protein superfamily also performs many other diverse functions. Yang et al. insightfully engineer a single mutation to unmask a cell signaling activity of tyrosyl-tRNA synthetase [1].
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页码：1307 / 1308
页数：2
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