New developments in the management of nasopharyngeal carcinoma

被引:12
作者
Blanchard, P. [1 ,2 ]
Nguyen, F. [1 ]
Moya-Plana, A. [3 ]
Pignon, J. P. [2 ,4 ]
Even, C. [3 ]
Bidault, F. [5 ]
Temam, S. [3 ]
Ruffier, A. [1 ]
Tao, Y. [1 ]
机构
[1] Gustave Roussy Canc Campus, Dept Radiotherapie Oncol, 114 Rue Edouard Valliant, F-94800 Villejuif, France
[2] Univ Paris Saclay, Unite Inserm 1018, CESP, F-94800 Villejuif, France
[3] Gustave Roussy Canc Campus, Dept Carcinol Cervicofaciale, F-94800 Villejuif, France
[4] Gustave Roussy Canc Campus, Serv Biostatist & Epidemiol, Plateforme LNCC Metaanal, F-94800 Villejuif, France
[5] Gustave Roussy Canc Campus, Serv Imagerie Med, F-94800 Villejuif, France
来源
CANCER RADIOTHERAPIE | 2018年 / 22卷 / 6-7期
关键词
Nasopharyngeal cancer; Chemotherapy; Epstein Barr virus; Meta-analysis; Radiotherapy; EPSTEIN-BARR-VIRUS; TARGET VOLUMES CTV; CONCURRENT CHEMORADIOTHERAPY; RADIOTHERAPY; DNA; CHEMOTHERAPY; MULTICENTER; DELINEATION; CANCER; TRIAL;
D O I
10.1016/j.canrad.2018.06.003
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Nasopharyngeal carcinoma is a rare condition, with less than 300 cases occurring per year in France. Its treatment can be difficult due to the importance of side effects, but tumor control is usually excellent following a well conducted chemoradiotherapy. This article summarizes the recent advances in nasopharyngeal cancer diagnosis, classification, treatment, surveillance and management of recurrences. Chemotherapy timing is discussed, along with arguments in favor of induction chemotherapy in locally advanced cases. As a survival advantage has been suggested for when patients are treated in high volume center it seems reasonable to refer these young patients for treatment to tertiary expert centers, especially given the low incidence of the disease. (C) 2018 Societe francaise de radiotherapie oncologique (SFRO). Published by Elsevier Masson SAS. All rights reserved.
引用
收藏
页码:492 / 495
页数:4
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