Background. Dual-energy computed tomography (DEC'') has been widely used due to improved substances identification from additional spectral information. The quality of material-specific image produced by DECT attaches great importance to the elaborated design of the basis material decomposition method. Objective.1 he aim of this work is to develop and validate a data-driven algorithm for the image-based decomposition problem. Methods. A deep neural net, consisting of a fully convolutional net (FCN) and a fully connected net, is proposed to solve the material decomposition problem. The former net extracts the feature representation of input reconstructed images, and the latter net calculates the decomposed basic material coefficients from the joint feature vector. The whole model was trained and tested using a modified clinical dataset. Results. The proposed FCN delivers image with about 60% smaller bias and 70% lower standard deviation than the competing algorithms, suggesting its better material separation capability. Moreover, FCN still yields excellent performance in case of photon noise. Conclusions. Our deep cascaded network features high decomposition accuracies and noise robust property. The experimental results have shown the strong function fitting ability of the deep neural network. Deep learning paradigm could be a promising way to solve the nonlinear problem in DECT.
机构:
Univ Sci & Technol China, Hefei, Peoples R China
Chinese Acad Sci, Suzhou Inst Biomed Engn & Technol, Dept Med Imaging, Suzhou 215163, Peoples R ChinaUniv Sci & Technol China, Hefei, Peoples R China
Komolafe, Temitope E.
Du, Qiang
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Chinese Acad Sci, Suzhou Inst Biomed Engn & Technol, Dept Med Imaging, Suzhou 215163, Peoples R ChinaUniv Sci & Technol China, Hefei, Peoples R China
Du, Qiang
Zhang, Yin
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Chinese Acad Sci, Suzhou Inst Biomed Engn & Technol, Dept Med Imaging, Suzhou 215163, Peoples R ChinaUniv Sci & Technol China, Hefei, Peoples R China
Zhang, Yin
Wu, Zhongyi
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Chinese Acad Sci, Suzhou Inst Biomed Engn & Technol, Dept Med Imaging, Suzhou 215163, Peoples R ChinaUniv Sci & Technol China, Hefei, Peoples R China
Wu, Zhongyi
Zhang, Cheng
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Chinese Acad Sci, Suzhou Inst Biomed Engn & Technol, Dept Med Imaging, Suzhou 215163, Peoples R ChinaUniv Sci & Technol China, Hefei, Peoples R China
Zhang, Cheng
Li, Ming
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Chinese Acad Sci, Suzhou Inst Biomed Engn & Technol, Dept Med Imaging, Suzhou 215163, Peoples R ChinaUniv Sci & Technol China, Hefei, Peoples R China
Li, Ming
Zheng, Jian
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Chinese Acad Sci, Suzhou Inst Biomed Engn & Technol, Dept Med Imaging, Suzhou 215163, Peoples R ChinaUniv Sci & Technol China, Hefei, Peoples R China
Zheng, Jian
Yang, Xiaodong
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Chinese Acad Sci, Suzhou Inst Biomed Engn & Technol, Dept Med Imaging, Suzhou 215163, Peoples R ChinaUniv Sci & Technol China, Hefei, Peoples R China
机构:
Washington Univ, Sch Med, Dept Radiol, Mallinckrodt Inst Radiol, St Louis, MO 63110 USAWashington Univ, Sch Med, Dept Radiol, Mallinckrodt Inst Radiol, St Louis, MO 63110 USA
机构:
Department of Medical Imaging, Jincheng People's Hospital, Jincheng,048000, ChinaDepartment of Medical Imaging, Jincheng People's Hospital, Jincheng,048000, China
Tian, Xin
Chen, Yunbing
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Department of Medical Imaging, Jincheng People's Hospital, Jincheng,048000, ChinaDepartment of Medical Imaging, Jincheng People's Hospital, Jincheng,048000, China
Chen, Yunbing
Pan, Sancong
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机构:
Department of Cardiovascular Medicine, Jincheng People's Hospital, Jincheng,048000, ChinaDepartment of Medical Imaging, Jincheng People's Hospital, Jincheng,048000, China
Pan, Sancong
Lan, Honglin
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Department of Medical Imaging, Jincheng People's Hospital, Jincheng,048000, ChinaDepartment of Medical Imaging, Jincheng People's Hospital, Jincheng,048000, China
Lan, Honglin
Cheng, Lei
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The First Affiliated Hospital of Anhui Medical University, Hefei,230022, ChinaDepartment of Medical Imaging, Jincheng People's Hospital, Jincheng,048000, China
机构:
Jincheng Peoples Hosp, Dept Med Imaging, Jincheng 048000, Shanxi, Peoples R ChinaJincheng Peoples Hosp, Dept Med Imaging, Jincheng 048000, Shanxi, Peoples R China
Tian, Xin
Chen, Yunbing
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Jincheng Peoples Hosp, Dept Med Imaging, Jincheng 048000, Shanxi, Peoples R ChinaJincheng Peoples Hosp, Dept Med Imaging, Jincheng 048000, Shanxi, Peoples R China
Chen, Yunbing
Pan, Sancong
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机构:
Jincheng Peoples Hosp, Dept Cardiovasc Med, Jincheng 048000, Peoples R ChinaJincheng Peoples Hosp, Dept Med Imaging, Jincheng 048000, Shanxi, Peoples R China
Pan, Sancong
Lan, Honglin
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Jincheng Peoples Hosp, Dept Med Imaging, Jincheng 048000, Shanxi, Peoples R ChinaJincheng Peoples Hosp, Dept Med Imaging, Jincheng 048000, Shanxi, Peoples R China
Lan, Honglin
Cheng, Lei
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Anhui Med Univ, Dept Pediat, Affiliated Hosp 1, Hefei 230022, Peoples R ChinaJincheng Peoples Hosp, Dept Med Imaging, Jincheng 048000, Shanxi, Peoples R China
机构:
Massachusetts Gen Hosp, Dept Radiol, Abdominal Imaging Div, White 270,55 Fruit St, Boston, MA 02114 USAMassachusetts Gen Hosp, Dept Radiol, Abdominal Imaging Div, White 270,55 Fruit St, Boston, MA 02114 USA
Parakh, Anushri
Macri, Francesco
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Massachusetts Gen Hosp, Dept Radiol, Abdominal Imaging Div, White 270,55 Fruit St, Boston, MA 02114 USA
Univ Hosp Nimes, Dept Radiol, Pl Pr Debre, F-30029 Nimes, FranceMassachusetts Gen Hosp, Dept Radiol, Abdominal Imaging Div, White 270,55 Fruit St, Boston, MA 02114 USA
Macri, Francesco
Sahani, Dushyant
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Massachusetts Gen Hosp, Dept Radiol, Abdominal Imaging Div, White 270,55 Fruit St, Boston, MA 02114 USAMassachusetts Gen Hosp, Dept Radiol, Abdominal Imaging Div, White 270,55 Fruit St, Boston, MA 02114 USA