OPTIMIZATION OF MICROWAVE-ASSISTED EXTRACTION OF PHENOLIC COMPOUNDS FROM INULA BRITANNICA L. USING THE BOX-BEHNKEN DESIGN

被引:1
作者
Ivanova, Viktoria [1 ]
Trendafilova, Antoaneta [1 ]
机构
[1] Bulgarian Acad Sci, Ctr Phytochem, Inst Organ Chem, Sofia 1113, Bulgaria
关键词
Inula britannica L; phenolic compounds; microwave-assisted extraction; Box-Behnken design; ANTIOXIDANT; METABOLITES; PROFILE;
D O I
10.20450/mjcce.2022.2483
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A closed-vessel microwave-assisted extraction (MAE) of phenolic compounds from the aerial parts of Inula britannica L. using single-factor experiments and the Box-Behnken design with four independent variables (liquid-to-solid ratio, ethanol concentration, extraction time, and temperature) was investigated. The ANOVA results showed that the obtained model was significant at a 95 % confidence level. The extraction parameters for the maximal total phenolic content (46.19 mg GAE/g DM) were determined to be 15.13 ml/g liquid-to-solid ratio, 55.95 % EtOH, 73.74 degrees C, and 5.73 min. Compared with classical maceration, the proposed MAE of phenolic compounds from I. britannica saves a lot of time and gives a high extraction yield.
引用
收藏
页码:111 / 117
页数:7
相关论文
共 25 条
[1]   Microwave-assisted extraction of phenolic compounds from Carica papaya leaves: An optimization study and LC-QTOF-MS analysis [J].
Alara, Oluwaseun Ruth ;
Abdurahman, Nour Hamid ;
Ali, Hassan Alsaggaf ;
Zain, Norashikin Mat .
FUTURE FOODS, 2021, 3
[2]   Optimizing Microwave-Assisted Extraction Conditions to Obtain Phenolic-Rich Extract from Chromolaena odorata Leaves [J].
Alara, Oluwaseun Ruth ;
Abdurahman, Nour Hamid ;
Mudalip, Siti Kholijah Abdul .
CHEMICAL ENGINEERING & TECHNOLOGY, 2019, 42 (09) :1733-1740
[3]   Vernonia cinerea leaves as the source of phenolic compounds, antioxidants, and anti-diabetic activity using microwave-assisted extraction technique [J].
Alara, Oluwaseun Ruth ;
Abdurahman, Nour Hamid ;
Ukaegbu, Chinonso Ishmael ;
Azhari, Nour Hamid .
INDUSTRIAL CROPS AND PRODUCTS, 2018, 122 :533-544
[4]   Microwave-assisted extractions of active ingredients from plants [J].
Chan, Chung-Hung ;
Yusoff, Rozita ;
Ngoh, Gek-Cheng ;
Kung, Fabian Wai-Lee .
JOURNAL OF CHROMATOGRAPHY A, 2011, 1218 (37) :6213-6225
[5]   Phenolic compounds: from plants to foods [J].
Cheynier, Veronique .
PHYTOCHEMISTRY REVIEWS, 2012, 11 (2-3) :153-177
[6]   The Role of Polyphenols in Human Health and Food Systems: A Mini-Review [J].
Cory, Hannah ;
Passarelli, Simone ;
Szeto, John ;
Tamez, Martha ;
Mattei, Josiemer .
FRONTIERS IN NUTRITION, 2018, 5
[7]   Plant Phenolics: Extraction, Analysis and Their Antioxidant and Anticancer Properties [J].
Dai, Jin ;
Mumper, Russell J. .
MOLECULES, 2010, 15 (10) :7313-7352
[8]   A Brief Understanding of Process Optimisation in Microwave-assisted Extraction of Botanical Materials: Options and Opportunities with Chemometric Tools [J].
Das, Anup Kumar ;
Mandal, Vivekananda ;
Mandal, Subhash C. .
PHYTOCHEMICAL ANALYSIS, 2014, 25 (01) :1-12
[9]   Box-Behnken design: An alternative for the optimization of analytical methods [J].
Ferreira, S. L. C. ;
Bruns, R. E. ;
Ferreira, H. S. ;
Matos, G. D. ;
David, J. M. ;
Brandao, G. C. ;
da Silva, E. G. P. ;
Portugal, L. A. ;
dos Reis, P. S. ;
Souza, A. S. ;
dos Santos, W. N. L. .
ANALYTICA CHIMICA ACTA, 2007, 597 (02) :179-186
[10]  
Herrero M., 2012, COMPREHENSIVE SAMPLI, P159, DOI DOI 10.1016/B978-0-12-381373-2.00132-0