Changes in parameters of oxidative stress and free iron biomarkers during treatment with deferasirox in iron-overloaded patients with myelodysplastic syndromes

被引：75

作者：

Ghoti, Hussam

Fibach, Eitan ^{[2
]}

Merkel, Drorit ^{[3
]}

Perez-Avraham, Galit ^{[4
]}

Grisariu, Sigal ^{[2
]}

Rachmilewitz, Eliezer A. ^{[1
]}

机构：

[1] Edith Wolfson Med Ctr, Dept Hematol, Holon, Israel

[2] Hadassah Hebrew Univ Med Ctr, Jerusalem, Israel

[3] Chaim Sheba Med Ctr, IL-52621 Tel Hashomer, Israel

[4] Soroka Univ Med Ctr, Beer Sheva, Israel

来源：

HAEMATOLOGICA-THE HEMATOLOGY JOURNAL | 2010年 / 95卷 / 08期

关键词：

iron overload; oxidative stress; myelodysplastic syndromes; reactive oxygen species; RED-BLOOD-CELLS; PLATELETS; PLASMA;

D O I：

10.3324/haematol.2010.024992

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：1433 / 1434

页数：2

共 12 条

[1] Red blood cells, platelets and polymorphonuclear neutrophils of patients with sickle cell disease exhibit oxidative stress that can be ameliorated by antioxidants [J].

Amer, J ;

Ghoti, H ;

Rachmilewitz, E ;

Koren, A ;

Levin, C ;

Fibach, E .

BRITISH JOURNAL OF HAEMATOLOGY, 2006, 132 (01) :108-113

[2] Intracellular labile iron [J].

Breuer, William ;

Shvartsman, Maya ;

Cabantchik, Z. Ioav .

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, 2008, 40 (03) :350-354

[3] LPI-labile plasma iron in iron overload [J].

Cabantchik, ZI ;

Breuer, W ;

Zanninelli, G ;

Cianciulli, R .

BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY, 2005, 18 (02) :277-287

[4] Iron: The fifth horseman of the apocalypse? [J].

DeLoughery, Thomas G. .

AMERICAN JOURNAL OF HEMATOLOGY, 2009, 84 (05) :263-264

[5] Oxidative stress in red blood cells, platelets and polymorphonuclear leukocytes from patients with myelodysplastic syndrome [J].

Ghoti, Hussam ;

Amer, Johnny ;

Winder, Asher ;

Rachmilewitz, Eliezer ;

Fibach, Eitan .

EUROPEAN JOURNAL OF HAEMATOLOGY, 2007, 79 (06) :463-467

[6]

GREENBERG PL, 2002, HEMATOLOGY AM SOC HE, V136, P61

[7] Management of anemia associated with myelodysplastic syndrome [J].

Hellström-Lindberg, E .

SEMINARS IN HEMATOLOGY, 2005, 42 (02) :S10-S13

[8] Pathophysiology of iron overload [J].

Hershko, C ;

Link, G ;

Cabantchik, I .

COOLEYS ANEMIA: SEVENTH SYMPOSIUM, 1998, 850 :191-201

[9] Redox state of glutathione in human plasma [J].

Jones, DP ;

Carlson, JL ;

Mody, VC ;

Cai, JY ;

Lynn, MJ ;

Sternberg, P .

FREE RADICAL BIOLOGY AND MEDICINE, 2000, 28 (04) :625-635

[10]

List AF, 2008, BLOOD, V112, P634

← 1 2 →