A high current density DC magnetohydrodynamic (MHD) micropump

被引:104
作者
Homsy, A
Koster, S
Eijkel, JCT
van den Berg, A
Lucklum, F
Verpoorte, E
de Rooij, NF
机构
[1] Univ Neuchatel, Inst Microtechnol, CH-2000 Neuchatel, Switzerland
[2] Univ Twente, MESA Res Inst, Enschede, Netherlands
[3] Univ Groningen, Groningen Res Inst Pharm, NL-9700 AB Groningen, Netherlands
关键词
D O I
10.1039/b417892k
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
This paper describes the working principle of a DC magnetohydrodynamic (MHD) micropump that can be operated at high DC current densities (J) in 75-mu m-deep microfluidic channels without introducing gas bubbles into the pumping channel. The main design feature for current generation is a micromachined frit-like structure that connects the pumping channel to side reservoirs, where platinum electrodes are located. Current densities up to 4000 A m 22 could be obtained without noticeable Joule heating in the system. The pump performance was studied as a function of current density and magnetic field intensity, as well as buffer ionic strength and pH. Bead velocities of up to 1 mm s(-1) (0.5 mu L min(-1)) were observed in buffered solutions using a 0.4 T NdFeB permanent magnet, at an applied current density of 4000 A m(-2). This pump is intended for transport of electrolyte solutions having a relatively high ionic strength ( 0.5 - 1 M) in a DC magnetic field environment. The application of this pump for the study of biological samples in a miniaturized total analysis system (mu TAS) with integrated NMR detection is foreseen. In the 7 T NMR environment, a minimum 16-fold increase in volumetric flow rate for a given applied current density is expected.
引用
收藏
页码:466 / 471
页数:6
相关论文
共 23 条
  • [1] BAKER R., 1987, HDB ELECTROMAGNETIC
  • [2] Bao J.B., 2003, P 7 INT C MIN CHEM B, P407
  • [3] A magneto-hydrodynamically controlled fluidic network
    Bau, HH
    Zhu, JZ
    Qian, SZ
    Xiang, Y
    [J]. SENSORS AND ACTUATORS B-CHEMICAL, 2003, 88 (02) : 205 - 216
  • [4] A minute magneto hydro dynamic (MHD) mixer
    Bau, HH
    Zhong, JH
    Yi, MQ
    [J]. SENSORS AND ACTUATORS B-CHEMICAL, 2001, 79 (2-3) : 207 - 215
  • [5] The charge of glass and silica surfaces
    Behrens, SH
    Grier, DG
    [J]. JOURNAL OF CHEMICAL PHYSICS, 2001, 115 (14) : 6716 - 6721
  • [6] Campana AMG, 1998, J MICROCOLUMN SEP, V10, P339
  • [7] Davidson PA, 2001, INTRO MHD
  • [8] A circular ac magnetohydrodynamic micropump for chromatographic applications
    Eijkel, JCT
    Dalton, C
    Hayden, CJ
    Burt, JP
    Manz, A
    [J]. SENSORS AND ACTUATORS B-CHEMICAL, 2003, 92 (1-2) : 215 - 221
  • [9] FEYNMAN RP, 1964, FEYNMAN LECT PHYS, V2, pCH13
  • [10] Microfluidics - a review
    Gravesen, Peter
    Branebjerg, Jens
    Jensen, Ole Sondergard
    [J]. Journal of Micromechanics and Microengineering, 1993, 3 (04) : 168 - 182