Research progress in cation-π interactions

被引：27

作者：

Cheng JiaGao ^{[2
]}

Luo XiaoMin ^{[1
]}

Yan XiuHua ^{[1
]}

Li Zhong ^{[2
]}

Tang Yun ^{[2
]}

Jiang HuaLiang ^{[1
,2
]}

Zhu WeiLiang ^{[1
,3
]}

机构：

[1] Chinese Acad Sci, Shanghai Inst Mat Med, Drug Discovery & Design Ctr, Shanghai 201203, Peoples R China

[2] E China Univ Sci & Technol, Sch Pharm, Shanghai 200237, Peoples R China

[3] E China Univ Sci & Technol, Sch Sci, Shanghai 200237, Peoples R China

来源：

SCIENCE IN CHINA SERIES B-CHEMISTRY | 2008年 / 51卷 / 08期

基金：

中国国家自然科学基金;

关键词：

cation-pi interaction; intermolecular interaction; noncovalent interaction;

D O I：

10.1007/s11426-008-0082-8

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Cation-pi interaction is a potent intermolecular interaction between a cation and an aromatic system, which has been viewed as a new kind of binding force, as being compared with the classical interactions (e.g. hydrogen bonding, electrostatic and hydrophobic interactions). Cation-pi interactions have been observed in a wide range of biological contexts. In this paper, we present an overview of the typical cation-pi interactions in biological systems, the experimental and theoretical investigations on cation-pi interactions, as well as the research results on cation-pi interactions in our group.

引用

页码：709 / 717

页数：9

共 47 条

[1]

ALESHIN AE, 1994, J BIOL CHEM, V269, P15631

[2] Influence of substituents on cation-π interactions -: 5.: Absolute binding energies of alkali metal cation-anisole complexes determined by threshold collision-induced dissociation and theoretical studies [J].

Amunugama, R ;

Rodgers, MT .

INTERNATIONAL JOURNAL OF MASS SPECTROMETRY, 2003, 222 (1-3) :431-450

[3] Influence of substituents on cation-π interactions.: 1.: Absolute binding energies of alkali metal cation-toluene complexes determined by threshold collision-induced dissociation and theoretical studies [J].

Amunugama, R ;

Rodgers, MT .

JOURNAL OF PHYSICAL CHEMISTRY A, 2002, 106 (22) :5529-5539

[4] MAGNESIUM BINDING TO THE BACTERIAL CHEMOTAXIS PROTEIN CHEY RESULTS IN LARGE CONFORMATIONAL-CHANGES INVOLVING ITS FUNCTIONAL SURFACE [J].

BELLSOLELL, L ;

PRIETO, J ;

SERRANO, L ;

COLL, M .

JOURNAL OF MOLECULAR BIOLOGY, 1994, 238 (04) :489-495

[5] AMINO-AROMATIC INTERACTIONS IN PROTEINS [J].

BURLEY, SK ;

PETSKO, GA .

FEBS LETTERS, 1986, 203 (02) :139-143

[6] Cation sitting in aromatic cages:: ab initio computational studies on tetra methylammonium-(benzene)n (n=3-4) complexes [J].

Cheng, Jiagao ;

Gong, Zhen ;

Zhu, Weiliang ;

Tang, Yun ;

Li, Weihua ;

Li, Zhong ;

Jiang, Hualiang .

JOURNAL OF PHYSICAL ORGANIC CHEMISTRY, 2007, 20 (07) :448-453

[7] Effect of cation-π interaction on NMR:: A theoretical investigation on complexes of Li+, Na+, Be2+ and Mg2+ with aromatics [J].

Cheng, Jiagao ;

Zhu, Weiliang ;

Tang, Yun ;

Xu, Yufang ;

Li, Zhong ;

Chen, Kaixian ;

Jiang, Hualiang .

CHEMICAL PHYSICS LETTERS, 2006, 422 (4-6) :455-460

[8] Synthetic receptors as models for alkali metal cation-π binding sites in proteins [J].

De Wall, SL ;

Meadows, ES ;

Barbour, LJ ;

Gokel, GW .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (12) :6271-6276

[9] HUMAN GROWTH-HORMONE AND EXTRACELLULAR DOMAIN OF ITS RECEPTOR - CRYSTAL-STRUCTURE OF THE COMPLEX [J].

DEVOS, AM ;

ULTSCH, M ;

KOSSIAKOFF, AA .

SCIENCE, 1992, 255 (5042) :306-312

[10] The structure of the potassium channel:: Molecular basis of K+ conduction and selectivity [J].

Doyle, DA ;

Cabral, JM ;

Pfuetzner, RA ;

Kuo, AL ;

Gulbis, JM ;

Cohen, SL ;

Chait, BT ;

MacKinnon, R .

SCIENCE, 1998, 280 (5360) :69-77

← 1 2 3 4 5 →