Why do pulse pressure variations fail to predict the response to fluids in acute respiratory distress syndrome patients ventilated with low tidal volume?

被引:7
作者
De Backer, Daniel [1 ]
Scolletta, Sabino [1 ]
机构
[1] Univ Libre Bruxelles, Erasme Univ Hosp, Dept Intens Care, B-1070 Brussels, Belgium
来源
CRITICAL CARE | 2011年 / 15卷 / 02期
关键词
ACUTE LUNG INJURY; RESPONSIVENESS; OPTIMIZATION;
D O I
10.1186/cc10111
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Respiratory-associated variations in stroke volume and pulse pressure are frequently used to predict the response to fluid administration. However, it has been demonstrated that low tidal volume ventilation may limit their use in patients with acute respiratory distress syndrome (ARDS). In this issue, a trial investigates the value of pulse pressure variation to predict fluid responsiveness in a large series of patients with ARDS ventilated according to current guidelines.
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页数:2
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