Bio-inspired supramolecular materials by orthogonal self-assembly of hydrogelators and phospholipids

被引:54
作者
Boekhoven, J. [1 ,4 ]
Brizard, A. M. [1 ]
Stuart, M. C. A. [2 ]
Florusse, L. [1 ]
Raffy, G. [3 ]
Del Guerzo, A. [3 ]
van Esch, J. H. [1 ]
机构
[1] Delft Univ Technol, Dept Chem Engn, Julianalaan 136, NL-2628 BL Delft, Netherlands
[2] Univ Groningen, Stratingh Inst Chem, Nijenborgh 7, NL-9747 AG Groningen, Netherlands
[3] Univ Bordeaux, ISM, UMR 5255, 351 Cours Liberat, F-33400 Talence, France
[4] Tech Univ Munich, Dept Chem, Lichtenbergstr, D-485748 Garching, Germany
关键词
MOLECULAR-WEIGHT HYDROGELATORS; CATALYTIC CONTROL; GELS; TEMPERATURE; SURFACTANTS; TRANSITION; WATER; AMPHIPHILES; CHEMISTRY; LIPOSOMES;
D O I
10.1039/c6sc01021k
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The orthogonal self-assembly of multiple components is a powerful strategy towards the formation of complex biomimetic architectures, but so far the rules for designing such systems are unclear. Here we show how to identify orthogonal self-assembly at the supramolecular level and describe guidelines to achieve self-sorting in self-assembled mixed systems. By investigating multicomponent self-assembled systems consisting of low molecular weight gelators and phospholipids, both at a molecular and a supramolecular level, we found that orthogonal self-assembly can only take place if the entities assemble via a strong and distinct set of interactions. The resulting supramolecular architectures consist of fibrillar networks that coexist with liposomes and thereby provide additional levels of compartmentalization and enhanced stability as compared to self-assembled systems of gelators or phospholipids alone.
引用
收藏
页码:6021 / 6031
页数:11
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