ULTRASOUNDS-ASSISTED SYNTHESIS OF HIGHLY FUNCTIONALIZED ACETOPHENONE DERIVATIVES IN HETEROGENEOUS CATALYSIS

被引:0
|
作者
Zbancioc, Gheorghita N. [1 ]
Zbancioc, Ana Maria V. [2 ]
Mantu, Dorina [1 ]
Miron, Anca [2 ]
Tanase, Catalin [3 ]
Mangalagiu, Ionel I. [1 ]
机构
[1] Alexandru Ioan Cuza Univ, Fac Chem, Dept Organ Chem, Iasi 700506, Romania
[2] Gr T Popa Univ, Fac Farmacy Iasi, Iasi 700115, Romania
[3] Alexandru Ioan Cuza Univ, Fac Biochem, Iasi 700506, Romania
关键词
ultrasound; bromination; acetophenone; liquid phase; eco-friendly; ANTIMICROBIAL ACTIVITY; PYRIDAZINE DERIVATIVES; CHEMISTRY;
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A fast, general, environmentally friendly, and facile method for preparation of highly functionalized acetophenone derivatives under ultrasound irradiation in heterogeneous catalysis is presented. The ultrasound enhanced a remarkable rate of acceleration for bromination, the reaction time decrease significantly, reaction conditions are milder, the consumed energy decreases considerably and the amount of used solvents was reduced. Consequently, the ultrasounds-assisted bromination reaction could be considered eco-friendly. In the most cases under ultrasound irradiation the yields are higher, in some cases substantially. A comparative study, ultrasounds-conventional conditions was done.
引用
收藏
页码:983 / +
页数:6
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