Scintigraphy assessment of ischemic myocardial viability in patients with post-infarction left ventricular aneurysm

The study included 15 patients with coronary heart disease (CHD), post-infarction cardiosclerosis, and chronic left ventricular (LP) aneurysm. All patients underwent interventional myocardial revascularization and Dor aneurysmectomy. Myocardial scintigraphy with Tc-99m-MYOVIEW was performed at baseline (during nitroglycerine test and at rest), and 3-4 weeks after revascularization (at rest). According to baseline scintigraphy at rest data, 35% of the segments were hypoperfused, and in 20% the agent did not accumulate. After sublingual nitroglycerine administration, hypo- and non-perfused segment percentage reduced to 24% and 11%, respectively, after revascularization - to 24% and 11%. Single-photon emission computed tomography with Tc-99m-MYOVIEW, combined with sublingual nitroglycerin test, identifies viable myocardial zones in post-infarction LV aneurism area and might be used for predicting post-revascularization LF function recovery.