Iron Catalysis in Target Synthesis

被引：14

作者：

DaBell, Peter ^{[1
]}

Thomas, Stephen P. ^{[1
]}

机构：

[1] Univ Edinburgh, Sch Chem, Joseph Black Bldg, Edinburgh EH9 3FK, Midlothian, Scotland

来源：

SYNTHESIS-STUTTGART | 2020年 / 52卷 / 07期

基金：

英国工程与自然科学研究理事会;

关键词：

alkene functionalisation; carbocyclisation; cross-coupling; drug molecule synthesis; iron catalysis; natural product synthesis; oxidation; transition metal catalysis; CROSS-COUPLING REACTIONS; MEDIATED ENE CARBOCYCLIZATIONS; LITHIUM ALUMINUM-HYDRIDE; C-H AMINATION; GRIGNARD-REAGENTS; ALKYL-HALIDES; ENEDIENE CARBOCYCLIZATIONS; STEREOSELECTIVE-SYNTHESIS; DIOXYGEN ACTIVATION; STYRENE DERIVATIVES;

D O I：

10.1055/s-0039-1690813

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The use of iron-catalysed organic transformations in the total syntheses of natural products has increased significantly. Iron-catalysed cross-coupling reactions are now widely applied in total syntheses and many other transformations, such as alkene functionalisation, oxidation, and cyclisation. The development of these processes, as well as many examples of their use in target synthesis, is presented here. 1 Introduction 2 Cross-Coupling Reactions 3 Functionalisation of Unactivated Alkenes 4 Carbocyclisation Reactions 5 Oxidations 6 Further Examples 7 Conclusions

引用

页码：949 / 963

页数：15

共 110 条

[81]

Plietker B., 2008, IRON CATALYSIS ORGAN

[82] The Reincarnation of the Hieber Anion [Fe(CO)3(NO)]- - a New Venue in Nucleophilic Metal Catalysis [J].

Plietker, Bernd ;

Dieskaul, Andre .

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2009, 2009 (06) :775-787

[83] Dioxygen activation by enzymes with mononuclear non-heme iron active sites [J].

Que, L ;

Ho, RYN .

CHEMICAL REVIEWS, 1996, 96 (07) :2607-2624

[84] Biologically inspired oxidation catalysis [J].

Que, Lawrence, Jr. ;

Tolman, William B. .

NATURE, 2008, 455 (7211) :333-340

[85] A Ramberg-Backlund route to the stilbenoid anti-cancer agents combretastatin A-4 and DMU-212 [J].

Robinson, James E. ;

Taylor, Richard J. K. .

CHEMICAL COMMUNICATIONS, 2007, (16) :1617-1619

[86] Targeting delavirdine/atevirdine resistant HIV-1: Identification of (alkylamino)piperidine-containing bis(heteroaryl)piperazines as broad spectrum HIV-1 reverse transcriptase inhibitors [J].

Romero, DL ;

Olmsted, RA ;

Poel, TJ ;

Morge, RA ;

Biles, C ;

Keiser, BJ ;

Kopta, LA ;

Friis, JM ;

Hosley, JD ;

Stefanski, KJ ;

Wishka, DG ;

Evans, DB ;

Morris, J ;

Stehle, RG ;

Sharma, SK ;

Yagi, Y ;

Voorman, RL ;

Adams, WJ ;

Tarpley, WG ;

Thomas, RC .

JOURNAL OF MEDICINAL CHEMISTRY, 1996, 39 (19) :3769-3789

[87] A review of new developments in the Friedel-Crafts alkylation - From green chemistry to asymmetric catalysis [J].

Rueping, Magnus ;

Nachtsheim, Boris J. .

BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY, 2010, 6

[88] Asymmetric synthesis of salvinorin A, a potent κ opioid receptor agonist [J].

Scheerer, Jonathan R. ;

Lawrence, Jonathan F. ;

Wang, Grace C. ;

Evans, David A. .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2007, 129 (29) :8968-+

[89] Selective iron-catalyzed cross-coupling reactions of Grignard reagents with enol triflates, acid chlorides, and dichloroarenes [J].

Scheiper, B ;

Bonnekessel, M ;

Krause, H ;

Fürstner, A .

JOURNAL OF ORGANIC CHEMISTRY, 2004, 69 (11) :3943-3949

[90] Catalysis-based enantioselective total synthesis of the macrocyclic spermidine alkaloid isooncinotine [J].

Scheiper, B ;

Glorius, F ;

Leitner, A ;

Fürstner, A .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2004, 101 (33) :11960-11965

← 2 3 4 5 6 7 8 9 10 11 →