Nano Aluminium Nitride as a Solid Source of Ammonia for the Preparation of Hantzsch 1,4-Dihydropyridines and Bis-(1,4-dihydropyridines) in Water via One Pot Multicomponent Reaction

被引：43

作者：

Ghorbani-Choghamarani, Arash ^{[1
]}

Zolfigol, Mohammad Ali ^{[2
]}

Hajjami, Maryam ^{[2
]}

Goudarziafshar, Hamid ^{[1
]}

Nikoorazm, Mohsen ^{[1
]}

Yousefi, Somaieh ^{[1
]}

Tahmasbi, Bahman ^{[1
]}

机构：

[1] Ilam Univ, Fac Sci, Dept Chem, Ilam, Iran

[2] Bu Ali Sina Univ, Fac Chem, Hamadan, Iran

来源：

JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY | 2011年 / 22卷 / 03期

关键词：

1,4-dihydropyridine; bis-(1,4-dihydropyridine); ethyl acetoacetate; methyl acetoacetate; nano aluminium nitride; SOLVENT-FREE CONDITIONS; CONVENIENT SOURCE; MAGNESIUM NITRIDE; DERIVATIVES; OXIDE; DIHYDROPYRIDINES; TEMPERATURE; OXIDATION;

D O I：

10.1590/S0103-50532011000300016

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Nano aluminium nitride in the presence of water acts as solid source of ammonia, which is used for the preparation of 1,4-dihydropyridines and bis-(1,4-dihydropyridines). An efficient and simple procedure for the one-pot synthesis of 1,4-dihydropyridine and bis-(1,4-dihydropyridine) derivatives was achieved by combination of methyl acetoacetate or ethyl acetoacetate with aldehydes or dialdehydes and aluminium nitride at 80 degrees C in water in high purity and good yields.

引用

页码：525 / 531

页数：7

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