Upfront Surgery for Small Intestinal Non-Hodgkin's Lymphoma

被引：8

作者：

Iida, Tetsuhiro ^{[1
]}

Nozawa, Hiroaki ^{[1
]}

Sonoda, Hirofumi ^{[1
]}

Toyama, Kazuhiro ^{[2
]}

Kawai, Kazushige ^{[1
]}

Hata, Keisuke ^{[1
]}

Tanaka, Toshiaki ^{[1
]}

Nishikawa, Takeshi ^{[1
]}

Sasaki, Kazuhito ^{[1
]}

Shuno, Yasutaka ^{[1
]}

Kaneko, Manabu ^{[1
]}

Murono, Koji ^{[1
]}

Emoto, Shigenobu ^{[1
]}

Ishii, Hiroaki ^{[1
]}

Kurokawa, Mineo ^{[2
]}

Ishihara, Soichiro ^{[1
]}

机构：

[1] Univ Tokyo, Dept Surg Oncol, Tokyo, Japan

[2] Univ Tokyo, Dept Hematol & Oncol, Tokyo, Japan

来源：

ANTICANCER RESEARCH | 2020年 / 40卷 / 04期

基金：

日本学术振兴会;

关键词：

Small intestinal lymphoma; prevention of perforation; GASTROINTESTINAL-TRACT; CLASSIFICATION; MULTICENTER; CHOP;

D O I：

10.21873/anticanres.14206

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Background/Aim: The clinical significance of surgery for secondary small intestinal non-Hodgkin's lymphomas (NHL) remains unknown. This study aimed to investigate the efficacy of resection for both primary and secondary small intestinal NHL. Patients and Methods: Twenty patients with small intestinal lymphoma who underwent surgical resection at our Institute between 2009 and 2017 were retrospectively evaluated. The clinicopathological and surgery-related factors were reviewed. We also analyzed their surgical outcomes such as postoperative complications, perforation rate, and overall survival (OS). Results: In total, 13 (65%) and 7 (35%) patients had primary and secondary lymphomas, respectively. A total of 70% of patients were diagnosed with aggressive-type lymphomas. A total of 15 (75%) patients had Lugano system stage IV. Only one (5%) patient experienced postoperative grade II deep vein thrombosis and pulmonary embolism. The 3-year OS rate after surgery was 59.6%. Conclusion: Surgical resection prior to chemotherapy is a feasible and safe therapeutic strategy for small intestinal NHL.

引用

页码：2373 / 2377

页数：5

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